Designing smart biomaterials for tissue engineering

Ferdous Khan, Masaru Tanaka

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The engineering of human tissues to cure diseases is an interdisciplinary and a very attractive field of research both in academia and the biotechnology industrial sector. Three-dimensional (3D) biomaterial scaffolds can play a critical role in the development of new tissue morphogenesis via interacting with human cells. Although simple polymeric biomaterials can provide mechanical and physical properties required for tissue development, insufficient biomimetic property and lack of interactions with human progenitor cells remain problematic for the promotion of functional tissue formation. Therefore, the developments of advanced functional biomaterials that respond to stimulus could be the next choice to generate smart 3D biomimetic scaffolds, actively interacting with human stem cells and progenitors along with structural integrity to form functional tissue within a short period. To date, smart biomaterials are designed to interact with biological systems for a wide range of biomedical applications, from the delivery of bioactive molecules and cell adhesion mediators to cellular functioning for the engineering of functional tissues to treat diseases.

Original languageEnglish
Article number17
JournalInternational journal of molecular sciences
Volume19
Issue number1
DOIs
Publication statusPublished - Jan 1 2018

Fingerprint

tissue engineering
Biocompatible Materials
Tissue Engineering
Tissue engineering
Biomaterials
Tissue
Biomimetics
biomimetics
Stem Cells
Cell Engineering
engineering
Human Engineering
Cell Adhesion Molecules
Biotechnology
biotechnology
Morphogenesis
stem cells
Cell adhesion
promotion
Structural integrity

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

Designing smart biomaterials for tissue engineering. / Khan, Ferdous; Tanaka, Masaru.

In: International journal of molecular sciences, Vol. 19, No. 1, 17, 01.01.2018.

Research output: Contribution to journalArticle

@article{45dfe6ac8cda4f1c808c10fe79ffaeef,
title = "Designing smart biomaterials for tissue engineering",
abstract = "The engineering of human tissues to cure diseases is an interdisciplinary and a very attractive field of research both in academia and the biotechnology industrial sector. Three-dimensional (3D) biomaterial scaffolds can play a critical role in the development of new tissue morphogenesis via interacting with human cells. Although simple polymeric biomaterials can provide mechanical and physical properties required for tissue development, insufficient biomimetic property and lack of interactions with human progenitor cells remain problematic for the promotion of functional tissue formation. Therefore, the developments of advanced functional biomaterials that respond to stimulus could be the next choice to generate smart 3D biomimetic scaffolds, actively interacting with human stem cells and progenitors along with structural integrity to form functional tissue within a short period. To date, smart biomaterials are designed to interact with biological systems for a wide range of biomedical applications, from the delivery of bioactive molecules and cell adhesion mediators to cellular functioning for the engineering of functional tissues to treat diseases.",
author = "Ferdous Khan and Masaru Tanaka",
year = "2018",
month = "1",
day = "1",
doi = "10.3390/ijms19010017",
language = "English",
volume = "19",
journal = "International Journal of Molecular Sciences",
issn = "1661-6596",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "1",

}

TY - JOUR

T1 - Designing smart biomaterials for tissue engineering

AU - Khan, Ferdous

AU - Tanaka, Masaru

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The engineering of human tissues to cure diseases is an interdisciplinary and a very attractive field of research both in academia and the biotechnology industrial sector. Three-dimensional (3D) biomaterial scaffolds can play a critical role in the development of new tissue morphogenesis via interacting with human cells. Although simple polymeric biomaterials can provide mechanical and physical properties required for tissue development, insufficient biomimetic property and lack of interactions with human progenitor cells remain problematic for the promotion of functional tissue formation. Therefore, the developments of advanced functional biomaterials that respond to stimulus could be the next choice to generate smart 3D biomimetic scaffolds, actively interacting with human stem cells and progenitors along with structural integrity to form functional tissue within a short period. To date, smart biomaterials are designed to interact with biological systems for a wide range of biomedical applications, from the delivery of bioactive molecules and cell adhesion mediators to cellular functioning for the engineering of functional tissues to treat diseases.

AB - The engineering of human tissues to cure diseases is an interdisciplinary and a very attractive field of research both in academia and the biotechnology industrial sector. Three-dimensional (3D) biomaterial scaffolds can play a critical role in the development of new tissue morphogenesis via interacting with human cells. Although simple polymeric biomaterials can provide mechanical and physical properties required for tissue development, insufficient biomimetic property and lack of interactions with human progenitor cells remain problematic for the promotion of functional tissue formation. Therefore, the developments of advanced functional biomaterials that respond to stimulus could be the next choice to generate smart 3D biomimetic scaffolds, actively interacting with human stem cells and progenitors along with structural integrity to form functional tissue within a short period. To date, smart biomaterials are designed to interact with biological systems for a wide range of biomedical applications, from the delivery of bioactive molecules and cell adhesion mediators to cellular functioning for the engineering of functional tissues to treat diseases.

UR - http://www.scopus.com/inward/record.url?scp=85039711657&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85039711657&partnerID=8YFLogxK

U2 - 10.3390/ijms19010017

DO - 10.3390/ijms19010017

M3 - Article

C2 - 29267207

AN - SCOPUS:85039711657

VL - 19

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1661-6596

IS - 1

M1 - 17

ER -