Detecting postsurgical recurrent hepatocellular carcinoma with multiphasic helical computed tomography: Intrahepatic metastasis or multicentric occurrence?

Tsuyoshi Tajima, Kengo Yoshimitsu, Hiroyuki Irie, Hitoshi Aibe, Kenji Shinozaki, Akihiro Nishie, Hiroshi Honda, Mitsuo Shimada

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Objective: The aim of this study was to assess the computed tomography (CT) patterns of postoperative recurrent hepatocellular carcinoma (HCC). Methods: Of 84 patients with histologically proven HCC by hepatectomies, multiphasic helical CT demonstrated 54 HCC lesions of intrahepatic recurrence in 31 (37%) patients. The initial and final appearances of HCC on hepatic arterial phase images were retrospectively determined by the serial CT scans, which were compare with appearances of primary HCC. Results: The initial appearances of 54 recurrent HCCs were identical to the appearances of primary HCC in 41 (76%) lesions. Serial changes from the initial appearance to the final appearance of recurrent HCC were observed in 10 (42%) of 24 lesions. The 13 discordant lesions and the 10 lesions with altered lesion vascularity in our series implied that at least 43% were of multicentric occurrence. Conclusion: More than 40% of postoperative recurrent HCCs show intranodular hemodynamic changes. The incompatibility between CT findings of primary and recurrent HCCs implies that these tumors contain nodules of multicentric occurrence.

Original languageEnglish
Pages (from-to)42-50
Number of pages9
JournalJournal of computer assisted tomography
Volume29
Issue number1
DOIs
Publication statusPublished - Jan 2005

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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