Detecting postsurgical recurrent hepatocellular carcinoma with multiphasic helical computed tomography: Intrahepatic metastasis or multicentric occurrence?

Tsuyoshi Tajima, Kengo Yoshimitsu, Hiroyuki Irie, Hitoshi Aibe, Kenji Shinozaki, Akihiro Nishie, Hiroshi Honda, Mitsuo Shimada

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objective: The aim of this study was to assess the computed tomography (CT) patterns of postoperative recurrent hepatocellular carcinoma (HCC). Methods: Of 84 patients with histologically proven HCC by hepatectomies, multiphasic helical CT demonstrated 54 HCC lesions of intrahepatic recurrence in 31 (37%) patients. The initial and final appearances of HCC on hepatic arterial phase images were retrospectively determined by the serial CT scans, which were compare with appearances of primary HCC. Results: The initial appearances of 54 recurrent HCCs were identical to the appearances of primary HCC in 41 (76%) lesions. Serial changes from the initial appearance to the final appearance of recurrent HCC were observed in 10 (42%) of 24 lesions. The 13 discordant lesions and the 10 lesions with altered lesion vascularity in our series implied that at least 43% were of multicentric occurrence. Conclusion: More than 40% of postoperative recurrent HCCs show intranodular hemodynamic changes. The incompatibility between CT findings of primary and recurrent HCCs implies that these tumors contain nodules of multicentric occurrence.

Original languageEnglish
Pages (from-to)42-50
Number of pages9
JournalJournal of Computer Assisted Tomography
Volume29
Issue number1
DOIs
Publication statusPublished - Jan 1 2005

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Spiral Computed Tomography
Hepatocellular Carcinoma
Neoplasm Metastasis
Tomography
Hepatectomy
Hemodynamics
Recurrence
Liver
Neoplasms

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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Detecting postsurgical recurrent hepatocellular carcinoma with multiphasic helical computed tomography : Intrahepatic metastasis or multicentric occurrence? / Tajima, Tsuyoshi; Yoshimitsu, Kengo; Irie, Hiroyuki; Aibe, Hitoshi; Shinozaki, Kenji; Nishie, Akihiro; Honda, Hiroshi; Shimada, Mitsuo.

In: Journal of Computer Assisted Tomography, Vol. 29, No. 1, 01.01.2005, p. 42-50.

Research output: Contribution to journalArticle

Tajima, Tsuyoshi ; Yoshimitsu, Kengo ; Irie, Hiroyuki ; Aibe, Hitoshi ; Shinozaki, Kenji ; Nishie, Akihiro ; Honda, Hiroshi ; Shimada, Mitsuo. / Detecting postsurgical recurrent hepatocellular carcinoma with multiphasic helical computed tomography : Intrahepatic metastasis or multicentric occurrence?. In: Journal of Computer Assisted Tomography. 2005 ; Vol. 29, No. 1. pp. 42-50.
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abstract = "Objective: The aim of this study was to assess the computed tomography (CT) patterns of postoperative recurrent hepatocellular carcinoma (HCC). Methods: Of 84 patients with histologically proven HCC by hepatectomies, multiphasic helical CT demonstrated 54 HCC lesions of intrahepatic recurrence in 31 (37{\%}) patients. The initial and final appearances of HCC on hepatic arterial phase images were retrospectively determined by the serial CT scans, which were compare with appearances of primary HCC. Results: The initial appearances of 54 recurrent HCCs were identical to the appearances of primary HCC in 41 (76{\%}) lesions. Serial changes from the initial appearance to the final appearance of recurrent HCC were observed in 10 (42{\%}) of 24 lesions. The 13 discordant lesions and the 10 lesions with altered lesion vascularity in our series implied that at least 43{\%} were of multicentric occurrence. Conclusion: More than 40{\%} of postoperative recurrent HCCs show intranodular hemodynamic changes. The incompatibility between CT findings of primary and recurrent HCCs implies that these tumors contain nodules of multicentric occurrence.",
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AU - Aibe, Hitoshi

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AU - Honda, Hiroshi

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N2 - Objective: The aim of this study was to assess the computed tomography (CT) patterns of postoperative recurrent hepatocellular carcinoma (HCC). Methods: Of 84 patients with histologically proven HCC by hepatectomies, multiphasic helical CT demonstrated 54 HCC lesions of intrahepatic recurrence in 31 (37%) patients. The initial and final appearances of HCC on hepatic arterial phase images were retrospectively determined by the serial CT scans, which were compare with appearances of primary HCC. Results: The initial appearances of 54 recurrent HCCs were identical to the appearances of primary HCC in 41 (76%) lesions. Serial changes from the initial appearance to the final appearance of recurrent HCC were observed in 10 (42%) of 24 lesions. The 13 discordant lesions and the 10 lesions with altered lesion vascularity in our series implied that at least 43% were of multicentric occurrence. Conclusion: More than 40% of postoperative recurrent HCCs show intranodular hemodynamic changes. The incompatibility between CT findings of primary and recurrent HCCs implies that these tumors contain nodules of multicentric occurrence.

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