Detection and analysis of photothermal signal generated in capillary channel flow

Satoshi Hirashima, Hitoshi Katae, Akira Harata

    Research output: Contribution to journalArticle

    Abstract

    A photothermal signal from a liquid sample in a capillary channel flow is detected and analyzed to optimize experimental conditions of microfluidic devices used for separation. A theoretical model for photoinduced temperature increase and photothermal signal intensity generated by intensity-modulated cw excitation beams at a crossed-beam configuration is proposed. Four experimental parameters (probe beam offset, excitation beam chopping frequency, linear flow velocity, and excitation beam size) and physical properties of solvent mainly dominate the signal. The model well explains the photothermal signal obtained experimentally under low velocity and high chopping frequency conditions. The obtained results make it possible to optimize the experimental conditions for the highly sensitive detection of chemicals under flow conditions.

    Original languageEnglish
    Article number07GE04
    JournalJapanese Journal of Applied Physics
    Volume48
    Issue number7 PART 2
    DOIs
    Publication statusPublished - Jul 1 2009

    Fingerprint

    channel flow
    Channel flow
    Microfluidics
    Flow velocity
    Physical properties
    excitation
    Liquids
    microfluidic devices
    low speed
    Temperature
    flow velocity
    physical properties
    probes
    liquids
    configurations
    temperature

    All Science Journal Classification (ASJC) codes

    • Engineering(all)
    • Physics and Astronomy(all)

    Cite this

    Detection and analysis of photothermal signal generated in capillary channel flow. / Hirashima, Satoshi; Katae, Hitoshi; Harata, Akira.

    In: Japanese Journal of Applied Physics, Vol. 48, No. 7 PART 2, 07GE04, 01.07.2009.

    Research output: Contribution to journalArticle

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