Abstract
Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration.
| Original language | English |
|---|---|
| Article number | 5450768 |
| Journal | Stem Cells International |
| Volume | 2018 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
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All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology
Cite this
Detection, characterization, and clinical application of mesenchymal stem cells in periodontal ligament tissue. / Tomokiyo, Atsushi; Yoshida, Shinichiro; Hamano, Sayuri; Hasegawa, Daigaku; Sugii, Hideki; Maeda, Hidefumi.
In: Stem Cells International, Vol. 2018, 5450768, 01.01.2018.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Detection, characterization, and clinical application of mesenchymal stem cells in periodontal ligament tissue
AU - Tomokiyo, Atsushi
AU - Yoshida, Shinichiro
AU - Hamano, Sayuri
AU - Hasegawa, Daigaku
AU - Sugii, Hideki
AU - Maeda, Hidefumi
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration.
AB - Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration.
UR - http://www.scopus.com/inward/record.url?scp=85058940599&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85058940599&partnerID=8YFLogxK
U2 - 10.1155/2018/5450768
DO - 10.1155/2018/5450768
M3 - Review article
AN - SCOPUS:85058940599
VL - 2018
JO - Stem Cells International
JF - Stem Cells International
SN - 1687-9678
M1 - 5450768
ER -