Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen

Noritsugu Sakamoto, Ryo Yanagawa, Etsuro Ono, Hiroshi Kida, Mamoru Mori, Yoshiko Arimitsu, Kiyoto Akama, Jun Yasuda, Kimehiko Too

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.

Original languageEnglish
Pages (from-to)548-556
Number of pages9
JournalZentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A
Volume259
Issue number4
DOIs
Publication statusPublished - Jan 1 1985
Externally publishedYes

Fingerprint

Hemagglutination Tests
Hemagglutination
Leptospirosis
Agglutination
Antigens
Antibodies
Serum
Agglutination Tests
Proteins

All Science Journal Classification (ASJC) codes

  • Immunology

Cite this

Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen. / Sakamoto, Noritsugu; Yanagawa, Ryo; Ono, Etsuro; Kida, Hiroshi; Mori, Mamoru; Arimitsu, Yoshiko; Akama, Kiyoto; Yasuda, Jun; Too, Kimehiko.

In: Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A, Vol. 259, No. 4, 01.01.1985, p. 548-556.

Research output: Contribution to journalArticle

Sakamoto, Noritsugu ; Yanagawa, Ryo ; Ono, Etsuro ; Kida, Hiroshi ; Mori, Mamoru ; Arimitsu, Yoshiko ; Akama, Kiyoto ; Yasuda, Jun ; Too, Kimehiko. / Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen. In: Zentralblatt fur Bakteriologie Mikrobiologie und Hygiene - Abt. 1 Orig. A. 1985 ; Vol. 259, No. 4. pp. 548-556.
@article{88d9e5716f284a4c89d6fb4bbeea921c,
title = "Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen",
abstract = "Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.",
author = "Noritsugu Sakamoto and Ryo Yanagawa and Etsuro Ono and Hiroshi Kida and Mamoru Mori and Yoshiko Arimitsu and Kiyoto Akama and Jun Yasuda and Kimehiko Too",
year = "1985",
month = "1",
day = "1",
doi = "10.1016/S0176-6724(85)80087-0",
language = "English",
volume = "259",
pages = "548--556",
journal = "International Journal of Medical Microbiology",
issn = "1438-4221",
publisher = "Urban und Fischer Verlag GmbH und Co. KG",
number = "4",

}

TY - JOUR

T1 - Detection of Antibodies to Leptospiral Genus-Specific Antigen in Human and Animal Sera by Indirect Hemagglutination Test with a Partially Purified Genus-Specific Protein Antigen

AU - Sakamoto, Noritsugu

AU - Yanagawa, Ryo

AU - Ono, Etsuro

AU - Kida, Hiroshi

AU - Mori, Mamoru

AU - Arimitsu, Yoshiko

AU - Akama, Kiyoto

AU - Yasuda, Jun

AU - Too, Kimehiko

PY - 1985/1/1

Y1 - 1985/1/1

N2 - Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.

AB - Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests.

UR - http://www.scopus.com/inward/record.url?scp=0021803357&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021803357&partnerID=8YFLogxK

U2 - 10.1016/S0176-6724(85)80087-0

DO - 10.1016/S0176-6724(85)80087-0

M3 - Article

C2 - 4050200

AN - SCOPUS:0021803357

VL - 259

SP - 548

EP - 556

JO - International Journal of Medical Microbiology

JF - International Journal of Medical Microbiology

SN - 1438-4221

IS - 4

ER -