Detection of high levels of immunoreactive human beta-1 interferon in sera from HIV-infected patients

Tomonori Minagawa, Kazuya Mizuno, Seiko Hirano, Misako Asano, Akihiko Numata, Masashi Kohanawa, Akio Nakane, Kei Hachimori, Sigenori Tamagawa, Masayoshi Negishi, Shojiro Yamazaki, Yu ichiro Satoh

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

We have examined human interferon beta-1 (HuIFN-β1) levels in the sera from patients with various diseases by using a newly developed highly sensitive enzymelinked immunosorbent assay system (ELISA). High levels of HuIFN-β1 were detected in the sera from Human Immunodeficiency Virus-I (HIV-I) infected patients, especially of asymptomatic carriers. The serum level of HuIFN-β1 may be a good indicator of HIV-I infection and of other immunological disorders.

Original languageEnglish
Pages (from-to)iii-vii
JournalLife Sciences
Volume45
Issue number11
DOIs
Publication statusPublished - 1989
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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