Detection of taste substances using impedance change of phospholipid Langmuir-Blodgett membrane

Hideyuki Akiyama, Kiyoshi Toko, Kaoru Yamafuji

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Impedance changes in a phospholipid Langmuir-Blodgett (LB) membrane by several taste substances were measured. A recently developed multichannel taste sensor that uses lipid/polymer membranes responds to taste substances by the membrane potential change. The potential change is based on the change of a diffuse electric double layer near the membrane surface; the sensitivity to nonelectrolytes and weak electrolytes is lower than that to strong electrolytes. Although bitter substances include both electrolytes and nonelectrolytes, outputs of the taste sensor were quite different from each other. Therefore the "bitter" response of human gustatory sensation cannot be represented by the change of the diffuse electric double layer. In this work, most bitter substances were found to increase the resistance of the phospholipid LB membrane. This implies that the increase of membrane resistance is related to the generation of bitter taste in humans and that the sensing system based on impedance measurement is quite effective for the detection of bitterness.

Original languageEnglish
Pages (from-to)5516-5521
Number of pages6
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes
Volume35
Issue number10
Publication statusPublished - 1996

Fingerprint

taste
Phospholipids
impedance
membranes
Membranes
nonelectrolytes
Electrolytes
electrolytes
sensors
Sensors
impedance measurement
Lipids
lipids
output
sensitivity
polymers
Polymers

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy (miscellaneous)
  • Engineering(all)

Cite this

Detection of taste substances using impedance change of phospholipid Langmuir-Blodgett membrane. / Akiyama, Hideyuki; Toko, Kiyoshi; Yamafuji, Kaoru.

In: Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes, Vol. 35, No. 10, 1996, p. 5516-5521.

Research output: Contribution to journalArticle

@article{fe9c6ecf0dfc4322a1a14ffb3f9c70df,
title = "Detection of taste substances using impedance change of phospholipid Langmuir-Blodgett membrane",
abstract = "Impedance changes in a phospholipid Langmuir-Blodgett (LB) membrane by several taste substances were measured. A recently developed multichannel taste sensor that uses lipid/polymer membranes responds to taste substances by the membrane potential change. The potential change is based on the change of a diffuse electric double layer near the membrane surface; the sensitivity to nonelectrolytes and weak electrolytes is lower than that to strong electrolytes. Although bitter substances include both electrolytes and nonelectrolytes, outputs of the taste sensor were quite different from each other. Therefore the {"}bitter{"} response of human gustatory sensation cannot be represented by the change of the diffuse electric double layer. In this work, most bitter substances were found to increase the resistance of the phospholipid LB membrane. This implies that the increase of membrane resistance is related to the generation of bitter taste in humans and that the sensing system based on impedance measurement is quite effective for the detection of bitterness.",
author = "Hideyuki Akiyama and Kiyoshi Toko and Kaoru Yamafuji",
year = "1996",
language = "English",
volume = "35",
pages = "5516--5521",
journal = "Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes",
issn = "0021-4922",
publisher = "Institute of Physics",
number = "10",

}

TY - JOUR

T1 - Detection of taste substances using impedance change of phospholipid Langmuir-Blodgett membrane

AU - Akiyama, Hideyuki

AU - Toko, Kiyoshi

AU - Yamafuji, Kaoru

PY - 1996

Y1 - 1996

N2 - Impedance changes in a phospholipid Langmuir-Blodgett (LB) membrane by several taste substances were measured. A recently developed multichannel taste sensor that uses lipid/polymer membranes responds to taste substances by the membrane potential change. The potential change is based on the change of a diffuse electric double layer near the membrane surface; the sensitivity to nonelectrolytes and weak electrolytes is lower than that to strong electrolytes. Although bitter substances include both electrolytes and nonelectrolytes, outputs of the taste sensor were quite different from each other. Therefore the "bitter" response of human gustatory sensation cannot be represented by the change of the diffuse electric double layer. In this work, most bitter substances were found to increase the resistance of the phospholipid LB membrane. This implies that the increase of membrane resistance is related to the generation of bitter taste in humans and that the sensing system based on impedance measurement is quite effective for the detection of bitterness.

AB - Impedance changes in a phospholipid Langmuir-Blodgett (LB) membrane by several taste substances were measured. A recently developed multichannel taste sensor that uses lipid/polymer membranes responds to taste substances by the membrane potential change. The potential change is based on the change of a diffuse electric double layer near the membrane surface; the sensitivity to nonelectrolytes and weak electrolytes is lower than that to strong electrolytes. Although bitter substances include both electrolytes and nonelectrolytes, outputs of the taste sensor were quite different from each other. Therefore the "bitter" response of human gustatory sensation cannot be represented by the change of the diffuse electric double layer. In this work, most bitter substances were found to increase the resistance of the phospholipid LB membrane. This implies that the increase of membrane resistance is related to the generation of bitter taste in humans and that the sensing system based on impedance measurement is quite effective for the detection of bitterness.

UR - http://www.scopus.com/inward/record.url?scp=0030261151&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030261151&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0030261151

VL - 35

SP - 5516

EP - 5521

JO - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes

JF - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes

SN - 0021-4922

IS - 10

ER -