Detection of triazolam in skeletal remains buried for 4 years

K. Kudo, H. Sugie, N. Syoui, K. Kurihara, N. Jitsufuchi, T. Imamura, N. Ikeda

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Abstract

Analyses of the hypnotic triazolam from the remains of two human skeletons buried underground for 4 years were made for purposes of confirmation. The bone marrow and mummified muscle were digested with 2 M sodium hydroxide, efficiently extracted using a 3-step solvent extraction procedure, and selectively analyzed by gas chromatography/mass spectrometry with the negative ion chemical ionization mode. Estazolam was the internal standard used. Triazolam was detected in all the samples; the concentrations were 0.36 ng/g in the bone marrow of one victim, and 0.37 and 5.5 ng/g in the bone marrow and mummified muscle of the other victim. This method should prove useful for determination of triazolam in extensively decomposed bodies.

Original languageEnglish
Pages (from-to)281-283
Number of pages3
JournalInternational Journal of Legal Medicine
Volume110
Issue number5
DOIs
Publication statusPublished - Sep 1 1997

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

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    Kudo, K., Sugie, H., Syoui, N., Kurihara, K., Jitsufuchi, N., Imamura, T., & Ikeda, N. (1997). Detection of triazolam in skeletal remains buried for 4 years. International Journal of Legal Medicine, 110(5), 281-283. https://doi.org/10.1007/s004140050086