Detection of triazolam in skeletal remains buried for 4 years

Keiko Kudo, H. Sugie, N. Syoui, K. Kurihara, N. Jitsufuchi, T. Imamura, Noriaki Ikeda

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Analyses of the hypnotic triazolam from the remains of two human skeletons buried underground for 4 years were made for purposes of confirmation. The bone marrow and mummified muscle were digested with 2 M sodium hydroxide, efficiently extracted using a 3-step solvent extraction procedure, and selectively analyzed by gas chromatography/mass spectrometry with the negative ion chemical ionization mode. Estazolam was the internal standard used. Triazolam was detected in all the samples; the concentrations were 0.36 ng/g in the bone marrow of one victim, and 0.37 and 5.5 ng/g in the bone marrow and mummified muscle of the other victim. This method should prove useful for determination of triazolam in extensively decomposed bodies.

Original languageEnglish
Pages (from-to)281-283
Number of pages3
JournalInternational Journal of Legal Medicine
Volume110
Issue number5
DOIs
Publication statusPublished - Sep 1 1997

Fingerprint

Triazolam
Bone Marrow
Estazolam
Muscles
Sodium Hydroxide
Hypnotics and Sedatives
Skeleton
Gas Chromatography-Mass Spectrometry
Ions
Body Remains

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Kudo, K., Sugie, H., Syoui, N., Kurihara, K., Jitsufuchi, N., Imamura, T., & Ikeda, N. (1997). Detection of triazolam in skeletal remains buried for 4 years. International Journal of Legal Medicine, 110(5), 281-283. https://doi.org/10.1007/s004140050086

Detection of triazolam in skeletal remains buried for 4 years. / Kudo, Keiko; Sugie, H.; Syoui, N.; Kurihara, K.; Jitsufuchi, N.; Imamura, T.; Ikeda, Noriaki.

In: International Journal of Legal Medicine, Vol. 110, No. 5, 01.09.1997, p. 281-283.

Research output: Contribution to journalArticle

Kudo, K, Sugie, H, Syoui, N, Kurihara, K, Jitsufuchi, N, Imamura, T & Ikeda, N 1997, 'Detection of triazolam in skeletal remains buried for 4 years', International Journal of Legal Medicine, vol. 110, no. 5, pp. 281-283. https://doi.org/10.1007/s004140050086
Kudo K, Sugie H, Syoui N, Kurihara K, Jitsufuchi N, Imamura T et al. Detection of triazolam in skeletal remains buried for 4 years. International Journal of Legal Medicine. 1997 Sep 1;110(5):281-283. https://doi.org/10.1007/s004140050086
Kudo, Keiko ; Sugie, H. ; Syoui, N. ; Kurihara, K. ; Jitsufuchi, N. ; Imamura, T. ; Ikeda, Noriaki. / Detection of triazolam in skeletal remains buried for 4 years. In: International Journal of Legal Medicine. 1997 ; Vol. 110, No. 5. pp. 281-283.
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