Development and characterization of a novel porous β-TCP scaffold with a three-dimensional PLLA network structure for use in bone tissue engineering

T. Arahira, M. Maruta, S. Matsuya, M. Todo

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Abstract In the field of bone regenerative medicine, the need for artificial bone substitutes has been rapidly increasing, and various porous bioactive ceramics have been developed for use as bone substitutes. While materials such as β-tricalcium phosphate (β-TCP) have good oseteoconductivity, poly (l-lactide acid) (PLLA) has been shown to have good mechanical and physical properties. Therefore, the primary aim of this study was to fabricate a porous β-TCP scaffold with a PLLA network structure (β-TCP/PLLA) for use in bone tissue engineering. The fabricated β-TCP/PLLA scaffolds were characterized by their surface microstructures and compressive moduli. The results demonstrated that the structure of the PLLA membrane, such as pore size and thickness of membrane, could be changed by varying the concentration of PLLA.

Original languageEnglish
Article number18720
Pages (from-to)148-150
Number of pages3
JournalMaterials Letters
Volume152
DOIs
Publication statusPublished - Aug 1 2015

Fingerprint

tissue engineering
Tissue engineering
Scaffolds
bones
Bone
acids
Acids
Bone Substitutes
substitutes
membranes
Membranes
Scaffolds (biology)
activity (biology)
medicine
Pore size
dilactide
phosphates
Phosphates
Physical properties
physical properties

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Development and characterization of a novel porous β-TCP scaffold with a three-dimensional PLLA network structure for use in bone tissue engineering. / Arahira, T.; Maruta, M.; Matsuya, S.; Todo, M.

In: Materials Letters, Vol. 152, 18720, 01.08.2015, p. 148-150.

Research output: Contribution to journalArticle

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