TY - GEN
T1 - Development of a rotatable reagent cartridge for high-performance microvalve system on a centrifugal microfluidic device
AU - Kawai, Takayuki
AU - Naruishi, Nahoko
AU - Nagai, Hidenori
AU - Tanaka, Yoshihide
AU - Hagihara, Yoshihisa
AU - Yoshida, Yasukazu
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - This paper reports simplification of fluidic design of lab-on-a-CD (LabCD) with rotatable reagent cartridge (RRCs) which act as high-performance microvalves. RRC is a column-shaped tank with several reagent rooms, which can be rotated on the LabCD and release only the intended reagent to the connected channel. Compared with the conventional microvalves controlling only a single channel flow, our RRC can regulate multiple reagents. Thus, the RRC can reduce the numbers of valves, channels, and reservoirs to simplify the fluidic system. We demonstrated an enzymatic assay on the LabCD with RRCs, where quantitative analyses of L-lactate were achieved with R2 > 0.999.
AB - This paper reports simplification of fluidic design of lab-on-a-CD (LabCD) with rotatable reagent cartridge (RRCs) which act as high-performance microvalves. RRC is a column-shaped tank with several reagent rooms, which can be rotated on the LabCD and release only the intended reagent to the connected channel. Compared with the conventional microvalves controlling only a single channel flow, our RRC can regulate multiple reagents. Thus, the RRC can reduce the numbers of valves, channels, and reservoirs to simplify the fluidic system. We demonstrated an enzymatic assay on the LabCD with RRCs, where quantitative analyses of L-lactate were achieved with R2 > 0.999.
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M3 - Conference contribution
AN - SCOPUS:84907325565
SN - 9781632666246
T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
SP - 961
EP - 963
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Y2 - 27 October 2013 through 31 October 2013
ER -