Development of a rotatable reagent cartridge for high-performance microvalve system on a centrifugal microfluidic device

Takayuki Kawai, Nahoko Naruishi, Hidenori Nagai, Yoshihide Tanaka, Yoshihisa Hagihara, Yasukazu Yoshida

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper reports simplification of fluidic design of lab-on-a-CD (LabCD) with rotatable reagent cartridge (RRCs) which act as high-performance microvalves. RRC is a column-shaped tank with several reagent rooms, which can be rotated on the LabCD and release only the intended reagent to the connected channel. Compared with the conventional microvalves controlling only a single channel flow, our RRC can regulate multiple reagents. Thus, the RRC can reduce the numbers of valves, channels, and reservoirs to simplify the fluidic system. We demonstrated an enzymatic assay on the LabCD with RRCs, where quantitative analyses of L-lactate were achieved with R2 > 0.999.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages961-963
Number of pages3
ISBN (Print)9781632666246
Publication statusPublished - 2013
Externally publishedYes
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: Oct 27 2013Oct 31 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume2

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period10/27/1310/31/13

All Science Journal Classification (ASJC) codes

  • Bioengineering

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