Development of Highly Sensitive Biosensor for Explosive Substances

T. Onodera, D. Ravi Shankaran, R. Harada, N. Miura, T. Sakai, K. Matsumoto, J. Liang, K. Toko, T. Imato

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Explosive molecules that leak out of a landmine may have extremely low concentrations in soil or air. This chapter aims at the development of a highly sensitive biosensor to detect explosive molecules for landmine detection. A highly sensitive surface plasmon resonance-based immunosensor for detection of trisenitrophenol (TNP) functioning with indirect competitive method and displacement method was developed. The sensor detected TNP with the sensitivity of ppb level. In future, monoclonal antibodies to TNT and 2,4-dinitrotoluene (DNT) and a high-performance sampling system will be developed for a landmine detection system. Then one is going to try to detect TNT and DNT using the developed methods with the sampling system and antibodies.

Original languageEnglish
Title of host publicationSystems and Human Science - For Safety, Security and Dependability
PublisherElsevier
Pages287-295
Number of pages9
ISBN (Print)9780444518132
DOIs
Publication statusPublished - 2005

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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    Onodera, T., Shankaran, D. R., Harada, R., Miura, N., Sakai, T., Matsumoto, K., Liang, J., Toko, K., & Imato, T. (2005). Development of Highly Sensitive Biosensor for Explosive Substances. In Systems and Human Science - For Safety, Security and Dependability (pp. 287-295). Elsevier. https://doi.org/10.1016/B978-044451813-2/50023-3