Development of on-chip automatic cell sensing and ejection system

T. Kawahara, T. Mizunuma, H. Uvet, M. Hagiwara, Y. Yamanishi, F. Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

We succeeded in automatic dispensing of a single swine oocyte (φ=100 um) from a biochip to atmosphere using developed cell ejection system. The developed system is composed of a cell loader, an inkjet mechanism and a capacitance sensor to dispense a droplet with a single cell. The performance of the sensor and the inkjet were evaluated using the fabricated micro-fluidic chip. We succeeded in sensing the passage of microbeads and oocytes (<|)=50-100 um) with the velocity of over 6 mm/s using a capacitance sensor which was fabricated on a glass substrate by photolithography techniques. The advantages of proposed system were that composed of the reusable drive system and a disposable biochip.

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages1781-1783
Number of pages3
Publication statusPublished - Dec 1 2010
Externally publishedYes
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: Oct 3 2010Oct 7 2010

Publication series

Name14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Volume3

Other

Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
CountryNetherlands
CityGroningen
Period10/3/1010/7/10

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

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  • Cite this

    Kawahara, T., Mizunuma, T., Uvet, H., Hagiwara, M., Yamanishi, Y., & Arai, F. (2010). Development of on-chip automatic cell sensing and ejection system. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (pp. 1781-1783). (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Vol. 3).