Development of self-setting calcium hydroxide preparation using dicalcium phosphate anhydrous and sodium hydrogen phosphate aqueous solution

Mariko Nakamura, Kunio Ishikawa, Yasuhiro Yoshida, Kazuomi Suzuki, Toshio Yamamoto

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Although a calcium hydroxide preparation is widely used in dental clinics as a base liner and a root canal filling material, its very high basicity causes necrosis of the dental pulp and it does not set. In this study, we evaluated the feasibility of developing a calcium hydroxide preparation that has a good setting ability and a moderate basicity. The calcium hydroxide preparation examined showed a good setting ability and formed an apatitic mineral upon setting when dicalcium phosphate anhydrous (DCPA) powder was added and mixed with sodium hydrogen phosphate aqueous solution. Setting mechanism had a close relationship with apatite formation. As a result of the addition of DCPA, that is, acidic calcium phosphate, the calcium hydroxide preparation showed a relatively mild basicity when compared with the DCPA-free calcium hydroxide preparation. An animal study demonstrated that a calcium hydroxide preparation containing DCPA causes less inflammatory response at the initial stage and elicits faster secondary dentin formation than DCPA-free calcium hydroxide preparation. We concluded therefore that a calcium hydroxide preparation containing DCPA is a promising alternative to the calcium hydroxide preparation currently used in dental clinics.

Original languageEnglish
Pages (from-to)434-439
Number of pages6
JournalJournal of the Ceramic Society of Japan
Volume112
Issue number1308
DOIs
Publication statusPublished - Aug 2004

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Calcium Hydroxide
Hydrated lime
hydroxides
calcium
Hydrogen
phosphates
Phosphates
Sodium
sodium
aqueous solutions
preparation
hydrogen
Alkalinity
Root Canal Filling Materials
anhydrous dibasic calcium phosphate
Apatites
canals
calcium phosphates
necrosis
causes

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Chemistry(all)
  • Condensed Matter Physics
  • Materials Chemistry

Cite this

Development of self-setting calcium hydroxide preparation using dicalcium phosphate anhydrous and sodium hydrogen phosphate aqueous solution. / Nakamura, Mariko; Ishikawa, Kunio; Yoshida, Yasuhiro; Suzuki, Kazuomi; Yamamoto, Toshio.

In: Journal of the Ceramic Society of Japan, Vol. 112, No. 1308, 08.2004, p. 434-439.

Research output: Contribution to journalArticle

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AU - Yamamoto, Toshio

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