Diacetone glucose architecture as a chirality template. II.1 Versatile synthon for the chiral deuterium labeling and synthesis of all diastereoisomers of chirally monodeuterated glycerol

Katsumi Kakinuma, Yoshihisa Iihama, Izumi Takagi, Kouichi Ozawa, Noriaki Yamauchi, Nobutaka Imamura, Yasuaki Esumi, Masakazu Uramoto

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Chirally deuterated ethylene oxide derivatives attached to a diacetone glucose template were developed as new versatile synthons for chiral deuterium labeling. All four diastereoisomers of chirally monodeuterated glycerol were also synthesized by chirality transcription from the same template.

Original languageEnglish
Pages (from-to)3763-3774
Number of pages12
JournalTetrahedron
Volume48
Issue number18
DOIs
Publication statusPublished - 1992
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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