Diaminodiphenylmethane Derivatives as a New Chromogenic Hydrogen Donor in Peroxidase-Catalyzed Oxidation Reaction with Hydrogen Peroxide

Makoto Mizoguchi; Masanobu Shiga; Kazumi Sasamoto

doi:10.1248/cpb.41.620

Diaminodiphenylmethane Derivatives as a New Chromogenic Hydrogen Donor in Peroxidase-Catalyzed Oxidation Reaction with Hydrogen Peroxide

Makoto Mizoguchi, Masanobu Shiga, Kazumi Sasamoto

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

New chromogenic hydrogen donors (la—c) for peroxidase-catalyzed oxidation were synthesized and demonstrated to be potentially useful for spectrometric determination of hydrogen peroxide. Under oxidative conditions these compounds exhibit, without an additional component, intense blue colors at ca. 650 nm with higher sensitivities toward hydrogen peroxide than those of conventional reagents. The detection limit of hydrogen peroxide using these compounds was 0.1 μ_M under serum-free conditions.

Original language	English
Pages (from-to)	620-623
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	41
Issue number	3
DOIs	https://doi.org/10.1248/cpb.41.620
Publication status	Published - 1993
Externally published	Yes

All Science Journal Classification (ASJC) codes

Chemistry(all)
Drug Discovery

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abstract = "New chromogenic hydrogen donors (la—c) for peroxidase-catalyzed oxidation were synthesized and demonstrated to be potentially useful for spectrometric determination of hydrogen peroxide. Under oxidative conditions these compounds exhibit, without an additional component, intense blue colors at ca. 650 nm with higher sensitivities toward hydrogen peroxide than those of conventional reagents. The detection limit of hydrogen peroxide using these compounds was 0.1 μM under serum-free conditions.",

author = "Makoto Mizoguchi and Masanobu Shiga and Kazumi Sasamoto",

year = "1993",

doi = "10.1248/cpb.41.620",

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AU - Shiga, Masanobu

AU - Sasamoto, Kazumi

PY - 1993

Y1 - 1993

N2 - New chromogenic hydrogen donors (la—c) for peroxidase-catalyzed oxidation were synthesized and demonstrated to be potentially useful for spectrometric determination of hydrogen peroxide. Under oxidative conditions these compounds exhibit, without an additional component, intense blue colors at ca. 650 nm with higher sensitivities toward hydrogen peroxide than those of conventional reagents. The detection limit of hydrogen peroxide using these compounds was 0.1 μM under serum-free conditions.

AB - New chromogenic hydrogen donors (la—c) for peroxidase-catalyzed oxidation were synthesized and demonstrated to be potentially useful for spectrometric determination of hydrogen peroxide. Under oxidative conditions these compounds exhibit, without an additional component, intense blue colors at ca. 650 nm with higher sensitivities toward hydrogen peroxide than those of conventional reagents. The detection limit of hydrogen peroxide using these compounds was 0.1 μM under serum-free conditions.

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ER -

Diaminodiphenylmethane Derivatives as a New Chromogenic Hydrogen Donor in Peroxidase-Catalyzed Oxidation Reaction with Hydrogen Peroxide

Abstract

All Science Journal Classification (ASJC) codes

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