Dietary CLA and DHA modify skin properties in mice

Daichi Oikawa; Tomonori Nakanishi; Yoshinori Nakamura; Yukiko Takahashi; Takaya Yamamoto; Nobuya Shiba; Manabu Tobisa; Tomo Takagi; Hisao Iwamoto; Tetsuya Tachibana; Mitsuhiro Furuse

doi:10.1007/s11745-003-1105-x

Dietary CLA and DHA modify skin properties in mice

Daichi Oikawa, Tomonori Nakanishi, Yoshinori Nakamura, Yukiko Takahashi, Takaya Yamamoto, Nobuya Shiba, Manabu Tobisa, Tomo Takagi, Hisao Iwamoto, Tetsuya Tachibana, Mitsuhiro Furuse

Animal and Marine Bioresource Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collagen contents were detected among treatments, although the FA composition in the skin was altered depending upon the FA composition of the supplemented oils. Electron microscopy revealed that the subcutaneous tissue layers in the CLA and DHA groups were significantly thinner than that in the high linoleic acid group, whereas no differences in the thickness of dermis layers were observed among the three groups. These results suggest that skin properties in mice are readily modified by dietary FA sources within 4 wk of dietary oil supplementation.

Original language	English
Pages (from-to)	609-614
Number of pages	6
Journal	Lipids
Volume	38
Issue number	6
DOIs	https://doi.org/10.1007/s11745-003-1105-x
Publication status	Published - Jun 1 2003

All Science Journal Classification (ASJC) codes

Biochemistry
Organic Chemistry
Cell Biology

Access to Document

10.1007/s11745-003-1105-x

Cite this

@article{f9282dfb1db84d36b7a99ed6f66e3ce4,

title = "Dietary CLA and DHA modify skin properties in mice",

abstract = "This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collagen contents were detected among treatments, although the FA composition in the skin was altered depending upon the FA composition of the supplemented oils. Electron microscopy revealed that the subcutaneous tissue layers in the CLA and DHA groups were significantly thinner than that in the high linoleic acid group, whereas no differences in the thickness of dermis layers were observed among the three groups. These results suggest that skin properties in mice are readily modified by dietary FA sources within 4 wk of dietary oil supplementation.",

author = "Daichi Oikawa and Tomonori Nakanishi and Yoshinori Nakamura and Yukiko Takahashi and Takaya Yamamoto and Nobuya Shiba and Manabu Tobisa and Tomo Takagi and Hisao Iwamoto and Tetsuya Tachibana and Mitsuhiro Furuse",

year = "2003",

month = jun,

day = "1",

doi = "10.1007/s11745-003-1105-x",

language = "English",

volume = "38",

pages = "609--614",

journal = "Lipids",

issn = "0024-4201",

publisher = "Springer Verlag",

number = "6",

}

TY - JOUR

T1 - Dietary CLA and DHA modify skin properties in mice

AU - Oikawa, Daichi

AU - Nakanishi, Tomonori

AU - Nakamura, Yoshinori

AU - Takahashi, Yukiko

AU - Yamamoto, Takaya

AU - Shiba, Nobuya

AU - Tobisa, Manabu

AU - Takagi, Tomo

AU - Iwamoto, Hisao

AU - Tachibana, Tetsuya

AU - Furuse, Mitsuhiro

PY - 2003/6/1

Y1 - 2003/6/1

N2 - This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collagen contents were detected among treatments, although the FA composition in the skin was altered depending upon the FA composition of the supplemented oils. Electron microscopy revealed that the subcutaneous tissue layers in the CLA and DHA groups were significantly thinner than that in the high linoleic acid group, whereas no differences in the thickness of dermis layers were observed among the three groups. These results suggest that skin properties in mice are readily modified by dietary FA sources within 4 wk of dietary oil supplementation.

AB - This study investigated the influence of PUFA on the properties of mouse skin. Mice (3 wk old) were given free access to oils high in linoleic acid, CLA, or DHA for 4 wk. At the end of the experiment, their skins were compared by both biochemical and histological methods. No significant differences in lipid and collagen contents were detected among treatments, although the FA composition in the skin was altered depending upon the FA composition of the supplemented oils. Electron microscopy revealed that the subcutaneous tissue layers in the CLA and DHA groups were significantly thinner than that in the high linoleic acid group, whereas no differences in the thickness of dermis layers were observed among the three groups. These results suggest that skin properties in mice are readily modified by dietary FA sources within 4 wk of dietary oil supplementation.

UR - http://www.scopus.com/inward/record.url?scp=12444337496&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=12444337496&partnerID=8YFLogxK

U2 - 10.1007/s11745-003-1105-x

DO - 10.1007/s11745-003-1105-x

M3 - Article

C2 - 12934670

AN - SCOPUS:12444337496

SN - 0024-4201

VL - 38

SP - 609

EP - 614

JO - Lipids

JF - Lipids

IS - 6

ER -

Dietary CLA and DHA modify skin properties in mice

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this