Abstract
Background: Previous studies showed an inverse association between folate intake and depression. However, epidemiological evidence for folate intake and postpartum depression is unavailable. This prospective study examined the relationship of dietary consumption of folate and B vitamins during pregnancy with the risk of postpartum depression. Methods: Study subjects were 865 Japanese women. Dietary data were obtained during pregnancy from a validated self-administered diet history questionnaire. Postpartum depression was defined as present when subjects had an Edinburgh Postnatal Depression Scale score of 9 or higher between 2 and 9 months postpartum. Adjustment was made for age, gestation, parity, cigarette smoking, alcohol intake, family structure, family income, education, changes in diet in the previous 1 month, season when data at baseline were collected, body mass index, time of delivery before the second survey, medical problems in pregnancy, baby's sex, and baby's birth weight. Results: Postpartum depression developed in 121 subjects (14.0%) 2 to 9 months postpartum. There was no measurable association between intake of folate, cobalamin, or pyridoxine and the risk of postpartum depression. Compared with riboflavin intake in the first quartile, only riboflavin consumption in the third quartile was independently related to a decreased risk of postpartum depression (multivariate odds ratio: 0.53, 95% CI: 0.29-0.95, P for trend = 0.55). Limitations: Personal and family psychiatric history, sociocultural factors, and personal and family relations were not controlled for. The possibility of misclassification of dietary information during pregnancy should be considered. Conclusions: Our results suggest that moderate consumption of riboflavin may be protective against postpartum depression.
| Original language | English |
|---|---|
| Pages (from-to) | 133-138 |
| Number of pages | 6 |
| Journal | Journal of Affective Disorders |
| Volume | 96 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Nov 1 2006 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Clinical Psychology
- Psychiatry and Mental health
Cite this
Dietary folate and vitamins B12, B6, and B2 intake and the risk of postpartum depression in Japan : The Osaka Maternal and Child Health Study. / Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Yokoyama, Tetsuji; Ohya, Yukihiro; Fukushima, Wakaba; Saito, Kyoko; Ohfuji, Satoko; Kiyohara, Chikako; Hirota, Yoshio.
In: Journal of Affective Disorders, Vol. 96, No. 1-2, 01.11.2006, p. 133-138.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dietary folate and vitamins B12, B6, and B2 intake and the risk of postpartum depression in Japan
T2 - The Osaka Maternal and Child Health Study
AU - Miyake, Yoshihiro
AU - Sasaki, Satoshi
AU - Tanaka, Keiko
AU - Yokoyama, Tetsuji
AU - Ohya, Yukihiro
AU - Fukushima, Wakaba
AU - Saito, Kyoko
AU - Ohfuji, Satoko
AU - Kiyohara, Chikako
AU - Hirota, Yoshio
PY - 2006/11/1
Y1 - 2006/11/1
N2 - Background: Previous studies showed an inverse association between folate intake and depression. However, epidemiological evidence for folate intake and postpartum depression is unavailable. This prospective study examined the relationship of dietary consumption of folate and B vitamins during pregnancy with the risk of postpartum depression. Methods: Study subjects were 865 Japanese women. Dietary data were obtained during pregnancy from a validated self-administered diet history questionnaire. Postpartum depression was defined as present when subjects had an Edinburgh Postnatal Depression Scale score of 9 or higher between 2 and 9 months postpartum. Adjustment was made for age, gestation, parity, cigarette smoking, alcohol intake, family structure, family income, education, changes in diet in the previous 1 month, season when data at baseline were collected, body mass index, time of delivery before the second survey, medical problems in pregnancy, baby's sex, and baby's birth weight. Results: Postpartum depression developed in 121 subjects (14.0%) 2 to 9 months postpartum. There was no measurable association between intake of folate, cobalamin, or pyridoxine and the risk of postpartum depression. Compared with riboflavin intake in the first quartile, only riboflavin consumption in the third quartile was independently related to a decreased risk of postpartum depression (multivariate odds ratio: 0.53, 95% CI: 0.29-0.95, P for trend = 0.55). Limitations: Personal and family psychiatric history, sociocultural factors, and personal and family relations were not controlled for. The possibility of misclassification of dietary information during pregnancy should be considered. Conclusions: Our results suggest that moderate consumption of riboflavin may be protective against postpartum depression.
AB - Background: Previous studies showed an inverse association between folate intake and depression. However, epidemiological evidence for folate intake and postpartum depression is unavailable. This prospective study examined the relationship of dietary consumption of folate and B vitamins during pregnancy with the risk of postpartum depression. Methods: Study subjects were 865 Japanese women. Dietary data were obtained during pregnancy from a validated self-administered diet history questionnaire. Postpartum depression was defined as present when subjects had an Edinburgh Postnatal Depression Scale score of 9 or higher between 2 and 9 months postpartum. Adjustment was made for age, gestation, parity, cigarette smoking, alcohol intake, family structure, family income, education, changes in diet in the previous 1 month, season when data at baseline were collected, body mass index, time of delivery before the second survey, medical problems in pregnancy, baby's sex, and baby's birth weight. Results: Postpartum depression developed in 121 subjects (14.0%) 2 to 9 months postpartum. There was no measurable association between intake of folate, cobalamin, or pyridoxine and the risk of postpartum depression. Compared with riboflavin intake in the first quartile, only riboflavin consumption in the third quartile was independently related to a decreased risk of postpartum depression (multivariate odds ratio: 0.53, 95% CI: 0.29-0.95, P for trend = 0.55). Limitations: Personal and family psychiatric history, sociocultural factors, and personal and family relations were not controlled for. The possibility of misclassification of dietary information during pregnancy should be considered. Conclusions: Our results suggest that moderate consumption of riboflavin may be protective against postpartum depression.
UR - http://www.scopus.com/inward/record.url?scp=33749593943&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749593943&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2006.05.024
DO - 10.1016/j.jad.2006.05.024
M3 - Article
C2 - 16815556
AN - SCOPUS:33749593943
VL - 96
SP - 133
EP - 138
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
SN - 0165-0327
IS - 1-2
ER -