Dietary sorbose ameliorates obesity and hyperglycemia in gold thioglucose-injected obese mice

K. Kita, Y. Kitayama, K. Nagao, J. Hwangbo, Mitsuhiro Furuse, J. Okumura

Research output: Contribution to journalArticle

Abstract

The influence of dietary sorbose on hyperphagia, hyperglycemia and hyperinsulinemia in gold thioglucose (GTG)-injected obese mice was examined. Body weight of GTG-injected obese mice was decreased by feeding a sorbose diet. When GTG-injected obese mice were given the diet containing sorbose, food intake was significantly lower than that of intact normal mice given a sucrose diet. The reduction in body weight of GTG-injected obese mice given dietary sorbose may be due to the decrease in food intake. Blood glucose concentration in GTG-injected obese mice was decreased by feeding the sorbose diet to the level of intact normal mice given sucrose. Feeding the sorbose diet lowered plasma insulin concentration compared to the sucrose group. It is concluded that feeding sorbose ameliorates hyperphagia, hyperglycemia and hyperinsulinemia in GTG-injected obese mice.

Original languageEnglish
Pages (from-to)25-32
Number of pages8
JournalJournal of Applied Animal Research
Volume22
Issue number1
DOIs
Publication statusPublished - Jan 1 2002

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Aurothioglucose
Sorbose
sorbose
Obese Mice
hyperglycemia
Hyperglycemia
gold
obesity
Obesity
mice
Diet
Sucrose
Hyperphagia
overeating
Hyperinsulinism
diet
hyperinsulinemia
sucrose
Eating
food intake

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Dietary sorbose ameliorates obesity and hyperglycemia in gold thioglucose-injected obese mice. / Kita, K.; Kitayama, Y.; Nagao, K.; Hwangbo, J.; Furuse, Mitsuhiro; Okumura, J.

In: Journal of Applied Animal Research, Vol. 22, No. 1, 01.01.2002, p. 25-32.

Research output: Contribution to journalArticle

Kita, K. ; Kitayama, Y. ; Nagao, K. ; Hwangbo, J. ; Furuse, Mitsuhiro ; Okumura, J. / Dietary sorbose ameliorates obesity and hyperglycemia in gold thioglucose-injected obese mice. In: Journal of Applied Animal Research. 2002 ; Vol. 22, No. 1. pp. 25-32.
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