Dietary treatment of adrenoleukodystrophy

Satoshi Suzuki, Takuro Kobayashi, Ikuo Goto, Yoshigoro Kuroiwa

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Abstract

We treated two patients with adrenoleukodystrophy (ALD) with a diet that contained 0.636% lipids as soybean oil, and less than 0.01% of the total fatty acids were very-long-chain fatty acids (VLCFA). Although clinical improvement was not evident in either patient, the VLCFA levels of erythrocyte membranes and plasma decreased in patient 1; in particular, the C25:0 in erythrocyte membranes became normal. Therefore, the abnormal accumulation of VLCFA in ALD arises partially from the diet. The VLCFA-free diet should be beneficial in ALD.

Original languageEnglish
Pages (from-to)104-106
Number of pages3
JournalNeurology
Volume36
Issue number1
Publication statusPublished - Jan 1986

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All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Suzuki, S., Kobayashi, T., Goto, I., & Kuroiwa, Y. (1986). Dietary treatment of adrenoleukodystrophy. Neurology, 36(1), 104-106.