TY - JOUR
T1 - Differences of stimulated and unstimulated salivary flow rates in patients with dry mouth
AU - Hayashida, Jun Nosuke
AU - Minami, Sakae
AU - Moriyama, Masafumi
AU - Toyoshima, Takeshi
AU - Shinozaki, Shouichi
AU - Tanaka, Akihiko
AU - Maehara, Takashi
AU - Nakamura, Seiji
N1 - Funding Information:
This work was supported by a Grant-in-Aid (numbers: 23792354 and 26463013 ) from the Ministry of Education, Culture, Sports, Science, and Technology in Japan .
Publisher Copyright:
© 2014 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Purpose: The purpose of this study was to clarify the usefulness of noninvasive examination items such as sialometry and Visual Analog Scale (VAS) in distinguishing Sjögren's syndrome (SS) in dry mouth patients from neurogenic/neuropsychiatric disorders and drugs (DND). Patients and methods: The study cohort comprised 50 patients with SS and 28 patients with DND. The gum test and Saxon test for stimulated salivary flow rate (SSFR), the spitting test for unstimulated salivary flow rate (USFR) and VAS were performed in all the patients with dry mouth. Results: In SS patients, the SSFR (mean: gum test, 6.34 mL/10. min; Saxon test, 1.19 g/2. min) and USFR (0.61 mL/15. min) were decreased. In DND patients, the SSFR (gum test, 16.35. mL/10 min; Saxon test, 3.58 g/2 min) was within the normal range, but the USFR (0.90 mL/15 min) was decreased. In VAS, SS patients scored significantly higher in the items of "water-drinking at meals", "difficulty in swallowing", and "taste abnormality", while significantly lower in the item of "oral pain". Conclusion: These results suggest that the SSFR, USFR and VAS could be useful in distinguishing DND from SS.
AB - Purpose: The purpose of this study was to clarify the usefulness of noninvasive examination items such as sialometry and Visual Analog Scale (VAS) in distinguishing Sjögren's syndrome (SS) in dry mouth patients from neurogenic/neuropsychiatric disorders and drugs (DND). Patients and methods: The study cohort comprised 50 patients with SS and 28 patients with DND. The gum test and Saxon test for stimulated salivary flow rate (SSFR), the spitting test for unstimulated salivary flow rate (USFR) and VAS were performed in all the patients with dry mouth. Results: In SS patients, the SSFR (mean: gum test, 6.34 mL/10. min; Saxon test, 1.19 g/2. min) and USFR (0.61 mL/15. min) were decreased. In DND patients, the SSFR (gum test, 16.35. mL/10 min; Saxon test, 3.58 g/2 min) was within the normal range, but the USFR (0.90 mL/15 min) was decreased. In VAS, SS patients scored significantly higher in the items of "water-drinking at meals", "difficulty in swallowing", and "taste abnormality", while significantly lower in the item of "oral pain". Conclusion: These results suggest that the SSFR, USFR and VAS could be useful in distinguishing DND from SS.
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U2 - 10.1016/j.ajoms.2014.04.011
DO - 10.1016/j.ajoms.2014.04.011
M3 - Article
AN - SCOPUS:84930378219
SN - 2212-5558
VL - 27
SP - 96
EP - 101
JO - Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
JF - Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
IS - 1
ER -