Differential Diagnosis of Pancreatic Epidermoid Cyst Without a Solid Component (Residual Splenic Tissue) vs. Mucinous Cystic Neoplasm

Kosei Ishigami, Akihiro Nishie, Hiroyuki Irie, Yoshiki Asayama, yasuhiro ushijima, Yukihisa Takayama, Daisule Okamoto, nobuhiro fujita, Ohtsuka Takao, Tetsuhide Ito, Naoki Mochidome, Hiroshi Honda

Research output: Contribution to journalArticle

Abstract

Purpose: The purpose of this study was to clarify whether there are differences in imaging findings between pancreatic epidermoid cyst (EDC) without a solid component (residual splenic tissue) and mucinous cystic neoplasm (MCN). Materials and Methods: The study group consisted of histologically proven EDC (eight cases) and MCN (20 cases). CT and MRI findings were compared on the following imaging findings: the shape of the cystic lesions and the presence or absence of septum, calcification, and high-intensity fluid on T1- and diffusion-weighted images (b factor = 1000). The degree of contact with the pancreatic tail was compared between the EDCs and six of the MCNs at the edge of the pancreatic tail. Results: The EDCs were round (n = 3) or oval (n = 5), while the MCNs consisted of three round, five oval, six pear-like, and six multilobulated lesions (P < 0.05). Septum was present in 4 of 8 (50%) EDCs and 19 of 20 (95%) MCNs (P < 0.05). The presence of calcification (2 of 8 [25%] EDCs vs. 8 of 20 [40%] MCNs), high-intensity fluid on T1-weighted images (2 of 7 [29%] EDCs vs. 5 of 20 [25%] MCNs), and high-intensity fluid on diffusion-weighted images (5 of 7 [71%] EDCs vs. 5 of 20 [25%] MCNs) were not significantly different. The degree of contact with the pancreatic parenchyma was similar between the two types of lesions. Conclusion: Although the imaging findings for EDC without a solid component and MCN overlap, a pear-like or multilobulated shape may favor a diagnosis of MCN.

Original languageEnglish
Pages (from-to)91-97
Number of pages7
JournalJournal of Gastrointestinal Cancer
Volume50
Issue number1
DOIs
Publication statusPublished - Mar 15 2019

Fingerprint

Pancreatic Cyst
Epidermal Cyst
Differential Diagnosis
Pyrus
Neoplasms

All Science Journal Classification (ASJC) codes

  • Oncology
  • Gastroenterology

Cite this

Differential Diagnosis of Pancreatic Epidermoid Cyst Without a Solid Component (Residual Splenic Tissue) vs. Mucinous Cystic Neoplasm. / Ishigami, Kosei; Nishie, Akihiro; Irie, Hiroyuki; Asayama, Yoshiki; ushijima, yasuhiro; Takayama, Yukihisa; Okamoto, Daisule; fujita, nobuhiro; Takao, Ohtsuka; Ito, Tetsuhide; Mochidome, Naoki; Honda, Hiroshi.

In: Journal of Gastrointestinal Cancer, Vol. 50, No. 1, 15.03.2019, p. 91-97.

Research output: Contribution to journalArticle

@article{7ab5e394eafb4be4a6c352efbae72f8a,
title = "Differential Diagnosis of Pancreatic Epidermoid Cyst Without a Solid Component (Residual Splenic Tissue) vs. Mucinous Cystic Neoplasm",
abstract = "Purpose: The purpose of this study was to clarify whether there are differences in imaging findings between pancreatic epidermoid cyst (EDC) without a solid component (residual splenic tissue) and mucinous cystic neoplasm (MCN). Materials and Methods: The study group consisted of histologically proven EDC (eight cases) and MCN (20 cases). CT and MRI findings were compared on the following imaging findings: the shape of the cystic lesions and the presence or absence of septum, calcification, and high-intensity fluid on T1- and diffusion-weighted images (b factor = 1000). The degree of contact with the pancreatic tail was compared between the EDCs and six of the MCNs at the edge of the pancreatic tail. Results: The EDCs were round (n = 3) or oval (n = 5), while the MCNs consisted of three round, five oval, six pear-like, and six multilobulated lesions (P < 0.05). Septum was present in 4 of 8 (50{\%}) EDCs and 19 of 20 (95{\%}) MCNs (P < 0.05). The presence of calcification (2 of 8 [25{\%}] EDCs vs. 8 of 20 [40{\%}] MCNs), high-intensity fluid on T1-weighted images (2 of 7 [29{\%}] EDCs vs. 5 of 20 [25{\%}] MCNs), and high-intensity fluid on diffusion-weighted images (5 of 7 [71{\%}] EDCs vs. 5 of 20 [25{\%}] MCNs) were not significantly different. The degree of contact with the pancreatic parenchyma was similar between the two types of lesions. Conclusion: Although the imaging findings for EDC without a solid component and MCN overlap, a pear-like or multilobulated shape may favor a diagnosis of MCN.",
author = "Kosei Ishigami and Akihiro Nishie and Hiroyuki Irie and Yoshiki Asayama and yasuhiro ushijima and Yukihisa Takayama and Daisule Okamoto and nobuhiro fujita and Ohtsuka Takao and Tetsuhide Ito and Naoki Mochidome and Hiroshi Honda",
year = "2019",
month = "3",
day = "15",
doi = "10.1007/s12029-017-0035-6",
language = "English",
volume = "50",
pages = "91--97",
journal = "Journal of Gastrointestinal Cancer",
issn = "1941-6628",
publisher = "Humana Press",
number = "1",

}

TY - JOUR

T1 - Differential Diagnosis of Pancreatic Epidermoid Cyst Without a Solid Component (Residual Splenic Tissue) vs. Mucinous Cystic Neoplasm

AU - Ishigami, Kosei

AU - Nishie, Akihiro

AU - Irie, Hiroyuki

AU - Asayama, Yoshiki

AU - ushijima, yasuhiro

AU - Takayama, Yukihisa

AU - Okamoto, Daisule

AU - fujita, nobuhiro

AU - Takao, Ohtsuka

AU - Ito, Tetsuhide

AU - Mochidome, Naoki

AU - Honda, Hiroshi

PY - 2019/3/15

Y1 - 2019/3/15

N2 - Purpose: The purpose of this study was to clarify whether there are differences in imaging findings between pancreatic epidermoid cyst (EDC) without a solid component (residual splenic tissue) and mucinous cystic neoplasm (MCN). Materials and Methods: The study group consisted of histologically proven EDC (eight cases) and MCN (20 cases). CT and MRI findings were compared on the following imaging findings: the shape of the cystic lesions and the presence or absence of septum, calcification, and high-intensity fluid on T1- and diffusion-weighted images (b factor = 1000). The degree of contact with the pancreatic tail was compared between the EDCs and six of the MCNs at the edge of the pancreatic tail. Results: The EDCs were round (n = 3) or oval (n = 5), while the MCNs consisted of three round, five oval, six pear-like, and six multilobulated lesions (P < 0.05). Septum was present in 4 of 8 (50%) EDCs and 19 of 20 (95%) MCNs (P < 0.05). The presence of calcification (2 of 8 [25%] EDCs vs. 8 of 20 [40%] MCNs), high-intensity fluid on T1-weighted images (2 of 7 [29%] EDCs vs. 5 of 20 [25%] MCNs), and high-intensity fluid on diffusion-weighted images (5 of 7 [71%] EDCs vs. 5 of 20 [25%] MCNs) were not significantly different. The degree of contact with the pancreatic parenchyma was similar between the two types of lesions. Conclusion: Although the imaging findings for EDC without a solid component and MCN overlap, a pear-like or multilobulated shape may favor a diagnosis of MCN.

AB - Purpose: The purpose of this study was to clarify whether there are differences in imaging findings between pancreatic epidermoid cyst (EDC) without a solid component (residual splenic tissue) and mucinous cystic neoplasm (MCN). Materials and Methods: The study group consisted of histologically proven EDC (eight cases) and MCN (20 cases). CT and MRI findings were compared on the following imaging findings: the shape of the cystic lesions and the presence or absence of septum, calcification, and high-intensity fluid on T1- and diffusion-weighted images (b factor = 1000). The degree of contact with the pancreatic tail was compared between the EDCs and six of the MCNs at the edge of the pancreatic tail. Results: The EDCs were round (n = 3) or oval (n = 5), while the MCNs consisted of three round, five oval, six pear-like, and six multilobulated lesions (P < 0.05). Septum was present in 4 of 8 (50%) EDCs and 19 of 20 (95%) MCNs (P < 0.05). The presence of calcification (2 of 8 [25%] EDCs vs. 8 of 20 [40%] MCNs), high-intensity fluid on T1-weighted images (2 of 7 [29%] EDCs vs. 5 of 20 [25%] MCNs), and high-intensity fluid on diffusion-weighted images (5 of 7 [71%] EDCs vs. 5 of 20 [25%] MCNs) were not significantly different. The degree of contact with the pancreatic parenchyma was similar between the two types of lesions. Conclusion: Although the imaging findings for EDC without a solid component and MCN overlap, a pear-like or multilobulated shape may favor a diagnosis of MCN.

UR - http://www.scopus.com/inward/record.url?scp=85037337177&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85037337177&partnerID=8YFLogxK

U2 - 10.1007/s12029-017-0035-6

DO - 10.1007/s12029-017-0035-6

M3 - Article

C2 - 29218653

AN - SCOPUS:85037337177

VL - 50

SP - 91

EP - 97

JO - Journal of Gastrointestinal Cancer

JF - Journal of Gastrointestinal Cancer

SN - 1941-6628

IS - 1

ER -