Differential effects of five types of antipathogenic plant peptides on model membranes

Jose Manuel Martinez Caaveiro, Antonio Molina, Juan M. González-Mañas, Pablo Rodríguez-Palenzuela, Francisco García-Olmedo, Félix M. Goñi

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

The effects of five antipathogenic plant peptides, wheat α-thionin, potato PTH1 defensin, barley LTP2 lipid transfer protein, and potato tuber DL1 and DL2 defensins, have been tested against phospholipid vesicles (liposomes). Wheat thionin very actively induces aggregation and leakage of negatively charged vesicles. LTP2 displays the same activities, although to a limited extent. Under certain conditions PTH1 and DL2 induce vesicle aggregation, but not leakage. Potato defensin DL1 failed to show any effect on liposomes. The same peptides have been assayed against a plant pathogenic bacterium, both the membrane-active and -inactive compounds having efficient antibacterial action.

Original languageEnglish
Pages (from-to)338-342
Number of pages5
JournalFEBS Letters
Volume410
Issue number2-3
DOIs
Publication statusPublished - Jun 30 1997

Fingerprint

Defensins
Solanum tuberosum
Thionins
Membranes
Liposomes
Peptides
Triticum
Agglomeration
Hordeum
Phospholipids
Bacteria

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Martinez Caaveiro, J. M., Molina, A., González-Mañas, J. M., Rodríguez-Palenzuela, P., García-Olmedo, F., & Goñi, F. M. (1997). Differential effects of five types of antipathogenic plant peptides on model membranes. FEBS Letters, 410(2-3), 338-342. https://doi.org/10.1016/S0014-5793(97)00613-3

Differential effects of five types of antipathogenic plant peptides on model membranes. / Martinez Caaveiro, Jose Manuel; Molina, Antonio; González-Mañas, Juan M.; Rodríguez-Palenzuela, Pablo; García-Olmedo, Francisco; Goñi, Félix M.

In: FEBS Letters, Vol. 410, No. 2-3, 30.06.1997, p. 338-342.

Research output: Contribution to journalArticle

Martinez Caaveiro, JM, Molina, A, González-Mañas, JM, Rodríguez-Palenzuela, P, García-Olmedo, F & Goñi, FM 1997, 'Differential effects of five types of antipathogenic plant peptides on model membranes', FEBS Letters, vol. 410, no. 2-3, pp. 338-342. https://doi.org/10.1016/S0014-5793(97)00613-3
Martinez Caaveiro JM, Molina A, González-Mañas JM, Rodríguez-Palenzuela P, García-Olmedo F, Goñi FM. Differential effects of five types of antipathogenic plant peptides on model membranes. FEBS Letters. 1997 Jun 30;410(2-3):338-342. https://doi.org/10.1016/S0014-5793(97)00613-3
Martinez Caaveiro, Jose Manuel ; Molina, Antonio ; González-Mañas, Juan M. ; Rodríguez-Palenzuela, Pablo ; García-Olmedo, Francisco ; Goñi, Félix M. / Differential effects of five types of antipathogenic plant peptides on model membranes. In: FEBS Letters. 1997 ; Vol. 410, No. 2-3. pp. 338-342.
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