Abstract
Purpose The purpose of this study was to determine the factors that contribute to the differentiation between phyllodes tumors (PTs) and fibroadenomas (FAs) on MR imaging. Materials and methods This retrospective study included 19 PTs and 18 FAs with ≥2 cm diameter. The presence or absence of a capsule and internal septum, the extent of lobulation, and the apparent diffusion coefficient (ADC) values were determined. The presence or absence of a cystic component, the time-intensity curve, and the signal intensity on delayed-phase contrast-enhanced T1WI were also evaluated in 31 patients (16 PTs and 17 FAs) who underwent a contrast-enhanced study. Results Cystic components were seen in 10 of the 16 PTs (63%) and in 4 of the 17 FAs (24%; P = 0.03). The PTs showed strong lobulation more frequently compared to the FAs (14/19 [74%] vs. 7/18 [39%], respectively; P = 0.04). Though there was no significant difference, PT tended to be heterogeneous more frequently on the delayed phase of the contrast-enhanced T1WI compared to the FA (11/16 [69%] vs. 7/17 [41%], respectively). No significant difference was found in the other findings. Conclusions Although PTs and FAs show similar MR findings, the presence of a cystic component, strong lobulation, and heterogeneity on delayed-phase contrast-enhanced T1WI suggests a PT.
| Original language | English |
|---|---|
| Pages (from-to) | 1344-1349 |
| Number of pages | 6 |
| Journal | European Journal of Radiology |
| Volume | 83 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2014 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
Cite this
Differentiation between benign phyllodes tumors and fibroadenomas of the breast on MR imaging. / Kamitani, Takeshi; Matsuo, Yoshio; Yabuuchi, Hidetake; Fujita, Nobuhiro; Nagao, Michinobu; Kawanami, Satoshi; Yonezawa, Masato; Yamasaki, Yuzo; Tokunaga, Eriko; Kubo, Makoto; Yamamoto, Hidetaka; Honda, Hiroshi.
In: European Journal of Radiology, Vol. 83, No. 8, 08.2014, p. 1344-1349.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Differentiation between benign phyllodes tumors and fibroadenomas of the breast on MR imaging
AU - Kamitani, Takeshi
AU - Matsuo, Yoshio
AU - Yabuuchi, Hidetake
AU - Fujita, Nobuhiro
AU - Nagao, Michinobu
AU - Kawanami, Satoshi
AU - Yonezawa, Masato
AU - Yamasaki, Yuzo
AU - Tokunaga, Eriko
AU - Kubo, Makoto
AU - Yamamoto, Hidetaka
AU - Honda, Hiroshi
PY - 2014/8
Y1 - 2014/8
N2 - Purpose The purpose of this study was to determine the factors that contribute to the differentiation between phyllodes tumors (PTs) and fibroadenomas (FAs) on MR imaging. Materials and methods This retrospective study included 19 PTs and 18 FAs with ≥2 cm diameter. The presence or absence of a capsule and internal septum, the extent of lobulation, and the apparent diffusion coefficient (ADC) values were determined. The presence or absence of a cystic component, the time-intensity curve, and the signal intensity on delayed-phase contrast-enhanced T1WI were also evaluated in 31 patients (16 PTs and 17 FAs) who underwent a contrast-enhanced study. Results Cystic components were seen in 10 of the 16 PTs (63%) and in 4 of the 17 FAs (24%; P = 0.03). The PTs showed strong lobulation more frequently compared to the FAs (14/19 [74%] vs. 7/18 [39%], respectively; P = 0.04). Though there was no significant difference, PT tended to be heterogeneous more frequently on the delayed phase of the contrast-enhanced T1WI compared to the FA (11/16 [69%] vs. 7/17 [41%], respectively). No significant difference was found in the other findings. Conclusions Although PTs and FAs show similar MR findings, the presence of a cystic component, strong lobulation, and heterogeneity on delayed-phase contrast-enhanced T1WI suggests a PT.
AB - Purpose The purpose of this study was to determine the factors that contribute to the differentiation between phyllodes tumors (PTs) and fibroadenomas (FAs) on MR imaging. Materials and methods This retrospective study included 19 PTs and 18 FAs with ≥2 cm diameter. The presence or absence of a capsule and internal septum, the extent of lobulation, and the apparent diffusion coefficient (ADC) values were determined. The presence or absence of a cystic component, the time-intensity curve, and the signal intensity on delayed-phase contrast-enhanced T1WI were also evaluated in 31 patients (16 PTs and 17 FAs) who underwent a contrast-enhanced study. Results Cystic components were seen in 10 of the 16 PTs (63%) and in 4 of the 17 FAs (24%; P = 0.03). The PTs showed strong lobulation more frequently compared to the FAs (14/19 [74%] vs. 7/18 [39%], respectively; P = 0.04). Though there was no significant difference, PT tended to be heterogeneous more frequently on the delayed phase of the contrast-enhanced T1WI compared to the FA (11/16 [69%] vs. 7/17 [41%], respectively). No significant difference was found in the other findings. Conclusions Although PTs and FAs show similar MR findings, the presence of a cystic component, strong lobulation, and heterogeneity on delayed-phase contrast-enhanced T1WI suggests a PT.
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U2 - 10.1016/j.ejrad.2014.04.031
DO - 10.1016/j.ejrad.2014.04.031
M3 - Article
C2 - 24856515
AN - SCOPUS:84903582406
VL - 83
SP - 1344
EP - 1349
JO - European Journal of Radiology
JF - European Journal of Radiology
SN - 0720-048X
IS - 8
ER -