Background: Multiple DnaA molecules form highly ordered complexes on the origin DNA to initiate chromosomal replication. Results: Novel structural motifs of DnaA are specifically required for the formation of the DNA unwinding-specific DnaA subcomplex. Conclusion: Distinct inter-DnaA interactions are required for the unwinding-specific subcomplex. Significance: Differentiation of the unwinding-specific subcomplex and a key mechanism underlying it are revealed.
|Number of pages||14|
|Journal||Journal of Biological Chemistry|
|Publication status||Published - Oct 26 2012|
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology