Diffuse-type gastric cancer: specific enhancement pattern on multiphasic contrast-enhanced computed tomography

Daisuke Tsurumaru, mitsutoshi miyasaka, Toshio Muraki, Yoshiki Asayama, Akihiro Nishie, Eiji Oki, Minako Hirahashi, Tomoyuki Hida, Hiroshi Honda

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: To evaluate the enhancement pattern of diffuse-type gastric cancers (DGCs) on multiphasic contrast-enhanced computed tomography gastrography (CECTG). Methods and materials: We studied 21 consecutive clinically diagnosed DGC patients who underwent CECTG. Gastric distension was obtained using effervescent granules. CT images were obtained 40 s (arterial phase) and 240 s (delayed phase) after injection of a nonionic contrast material. Two radiologists reviewed the CT images and analyzed layers and enhancement patterns. The readers evaluated the enhancement degree (mild, moderate, or marked) and calculated CT attenuation values by placing circular regions of interest (ROIs) within each layer of the lesion. The CT findings of 11 operated cases were correlated with pathological results. Results: Most lesions were double-layered in the arterial phase, with a moderately enhanced inner layer and a mildly enhanced outer layer, and single-layered in the delayed phase. The mean attenuation value of the inner layer (146 ± 32.8 HU) was significantly higher than that of the outer layer (80.4 ± 15.5 HU) in the arterial phase (p = 0.0001). In the pathological analysis, wall stratification was preserved in nine cases and not preserved in two cases. Conclusion: Most DGCs showed a double-layered pattern in the arterial phase and a single-layered pattern with moderate enhancement in the delayed phase.

Original languageEnglish
Pages (from-to)289-295
Number of pages7
JournalJapanese Journal of Radiology
Volume35
Issue number6
DOIs
Publication statusPublished - Jun 1 2017

Fingerprint

Stomach Neoplasms
Tomography
Contrast Media
Stomach
Injections
Radiologists

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Diffuse-type gastric cancer : specific enhancement pattern on multiphasic contrast-enhanced computed tomography. / Tsurumaru, Daisuke; miyasaka, mitsutoshi; Muraki, Toshio; Asayama, Yoshiki; Nishie, Akihiro; Oki, Eiji; Hirahashi, Minako; Hida, Tomoyuki; Honda, Hiroshi.

In: Japanese Journal of Radiology, Vol. 35, No. 6, 01.06.2017, p. 289-295.

Research output: Contribution to journalArticle

Tsurumaru, Daisuke ; miyasaka, mitsutoshi ; Muraki, Toshio ; Asayama, Yoshiki ; Nishie, Akihiro ; Oki, Eiji ; Hirahashi, Minako ; Hida, Tomoyuki ; Honda, Hiroshi. / Diffuse-type gastric cancer : specific enhancement pattern on multiphasic contrast-enhanced computed tomography. In: Japanese Journal of Radiology. 2017 ; Vol. 35, No. 6. pp. 289-295.
@article{4a9c004b544c4217aff48d4a052774a7,
title = "Diffuse-type gastric cancer: specific enhancement pattern on multiphasic contrast-enhanced computed tomography",
abstract = "Purpose: To evaluate the enhancement pattern of diffuse-type gastric cancers (DGCs) on multiphasic contrast-enhanced computed tomography gastrography (CECTG). Methods and materials: We studied 21 consecutive clinically diagnosed DGC patients who underwent CECTG. Gastric distension was obtained using effervescent granules. CT images were obtained 40 s (arterial phase) and 240 s (delayed phase) after injection of a nonionic contrast material. Two radiologists reviewed the CT images and analyzed layers and enhancement patterns. The readers evaluated the enhancement degree (mild, moderate, or marked) and calculated CT attenuation values by placing circular regions of interest (ROIs) within each layer of the lesion. The CT findings of 11 operated cases were correlated with pathological results. Results: Most lesions were double-layered in the arterial phase, with a moderately enhanced inner layer and a mildly enhanced outer layer, and single-layered in the delayed phase. The mean attenuation value of the inner layer (146 ± 32.8 HU) was significantly higher than that of the outer layer (80.4 ± 15.5 HU) in the arterial phase (p = 0.0001). In the pathological analysis, wall stratification was preserved in nine cases and not preserved in two cases. Conclusion: Most DGCs showed a double-layered pattern in the arterial phase and a single-layered pattern with moderate enhancement in the delayed phase.",
author = "Daisuke Tsurumaru and mitsutoshi miyasaka and Toshio Muraki and Yoshiki Asayama and Akihiro Nishie and Eiji Oki and Minako Hirahashi and Tomoyuki Hida and Hiroshi Honda",
year = "2017",
month = "6",
day = "1",
doi = "10.1007/s11604-017-0631-1",
language = "English",
volume = "35",
pages = "289--295",
journal = "Japanese Journal of Radiology",
issn = "1867-1071",
publisher = "Springer Japan",
number = "6",

}

TY - JOUR

T1 - Diffuse-type gastric cancer

T2 - specific enhancement pattern on multiphasic contrast-enhanced computed tomography

AU - Tsurumaru, Daisuke

AU - miyasaka, mitsutoshi

AU - Muraki, Toshio

AU - Asayama, Yoshiki

AU - Nishie, Akihiro

AU - Oki, Eiji

AU - Hirahashi, Minako

AU - Hida, Tomoyuki

AU - Honda, Hiroshi

PY - 2017/6/1

Y1 - 2017/6/1

N2 - Purpose: To evaluate the enhancement pattern of diffuse-type gastric cancers (DGCs) on multiphasic contrast-enhanced computed tomography gastrography (CECTG). Methods and materials: We studied 21 consecutive clinically diagnosed DGC patients who underwent CECTG. Gastric distension was obtained using effervescent granules. CT images were obtained 40 s (arterial phase) and 240 s (delayed phase) after injection of a nonionic contrast material. Two radiologists reviewed the CT images and analyzed layers and enhancement patterns. The readers evaluated the enhancement degree (mild, moderate, or marked) and calculated CT attenuation values by placing circular regions of interest (ROIs) within each layer of the lesion. The CT findings of 11 operated cases were correlated with pathological results. Results: Most lesions were double-layered in the arterial phase, with a moderately enhanced inner layer and a mildly enhanced outer layer, and single-layered in the delayed phase. The mean attenuation value of the inner layer (146 ± 32.8 HU) was significantly higher than that of the outer layer (80.4 ± 15.5 HU) in the arterial phase (p = 0.0001). In the pathological analysis, wall stratification was preserved in nine cases and not preserved in two cases. Conclusion: Most DGCs showed a double-layered pattern in the arterial phase and a single-layered pattern with moderate enhancement in the delayed phase.

AB - Purpose: To evaluate the enhancement pattern of diffuse-type gastric cancers (DGCs) on multiphasic contrast-enhanced computed tomography gastrography (CECTG). Methods and materials: We studied 21 consecutive clinically diagnosed DGC patients who underwent CECTG. Gastric distension was obtained using effervescent granules. CT images were obtained 40 s (arterial phase) and 240 s (delayed phase) after injection of a nonionic contrast material. Two radiologists reviewed the CT images and analyzed layers and enhancement patterns. The readers evaluated the enhancement degree (mild, moderate, or marked) and calculated CT attenuation values by placing circular regions of interest (ROIs) within each layer of the lesion. The CT findings of 11 operated cases were correlated with pathological results. Results: Most lesions were double-layered in the arterial phase, with a moderately enhanced inner layer and a mildly enhanced outer layer, and single-layered in the delayed phase. The mean attenuation value of the inner layer (146 ± 32.8 HU) was significantly higher than that of the outer layer (80.4 ± 15.5 HU) in the arterial phase (p = 0.0001). In the pathological analysis, wall stratification was preserved in nine cases and not preserved in two cases. Conclusion: Most DGCs showed a double-layered pattern in the arterial phase and a single-layered pattern with moderate enhancement in the delayed phase.

UR - http://www.scopus.com/inward/record.url?scp=85014685914&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85014685914&partnerID=8YFLogxK

U2 - 10.1007/s11604-017-0631-1

DO - 10.1007/s11604-017-0631-1

M3 - Article

C2 - 28281045

AN - SCOPUS:85014685914

VL - 35

SP - 289

EP - 295

JO - Japanese Journal of Radiology

JF - Japanese Journal of Radiology

SN - 1867-1071

IS - 6

ER -