Diffusivity of intraorbital lymphoma vs. inflammation: comparison of single shot turbo spin echo and multishot echo planar imaging techniques

Akio Hiwatashi, Osamu Togao, Koji Yamashita, Kazufumi Kikuchi, Ryotaro Kamei, Hiroshi Yoshikawa, Atsushi Takemura, Hiroshi Honda

Research output: Contribution to journalArticle

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Abstract

Purpose: To compare the abilities of turbo spin-echo diffusion-weighted imaging (TSE DWI) and multi-shot echo planar DWI (MSh DWI) to discriminate orbital lymphoma from inflammatory lesions. Materials and methods: Twenty-nine patients with pathologically confirmed lymphomas and 39 patients with inflammation were imaged with a 3.0-T system. The apparent diffusion coefficient (ADC) of each lesion was measured. Signal intensities compared to normal grey matter on conventional imaging were also measured. Results: The ADCs derived from the TSE DWI of the lymphomas (0.68 ± 0.14 × 10−3 mm2/s) were significantly lower than those of the inflammation cases (1.04 ± 0.39 × 10−3 mm2/s; p < 0.001). The ADCs derived from MSh DWI could not be used to separate the lymphomas from the inflammation (1.16 ± 0.43 × 10−3 mm2/s vs. 1.36 ± 0.48 × 10−3 mm2/s; p = 0.06). Conventional sequences also could not separate the lymphomas from the inflammation (p > 0.05). The ROC analysis showed the best diagnostic performance with ADCs derived from TSE DWI (the area under the curve: AUC = 0.831) followed by ADC derived from MSh DWI (AUC = 0.633). Conclusion: The ADCs derived from TSE DWI might help to differentiate orbital lymphomas from inflammation. Key Points: • ADC of lymphoma was significantly lower than that of inflammation. • ADC derived from TSE DWI showed the best diagnostic performance. • This study was conducted by a 3-T MR scanner.

Original languageEnglish
Pages (from-to)325-330
Number of pages6
JournalEuropean Radiology
Volume28
Issue number1
DOIs
Publication statusPublished - Jan 1 2018

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Echo-Planar Imaging
Lymphoma
Inflammation
Area Under Curve
ROC Curve

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Diffusivity of intraorbital lymphoma vs. inflammation : comparison of single shot turbo spin echo and multishot echo planar imaging techniques. / Hiwatashi, Akio; Togao, Osamu; Yamashita, Koji; Kikuchi, Kazufumi; Kamei, Ryotaro; Yoshikawa, Hiroshi; Takemura, Atsushi; Honda, Hiroshi.

In: European Radiology, Vol. 28, No. 1, 01.01.2018, p. 325-330.

Research output: Contribution to journalArticle

Hiwatashi, Akio ; Togao, Osamu ; Yamashita, Koji ; Kikuchi, Kazufumi ; Kamei, Ryotaro ; Yoshikawa, Hiroshi ; Takemura, Atsushi ; Honda, Hiroshi. / Diffusivity of intraorbital lymphoma vs. inflammation : comparison of single shot turbo spin echo and multishot echo planar imaging techniques. In: European Radiology. 2018 ; Vol. 28, No. 1. pp. 325-330.
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