Dioxin concentration in the preserved umbilical cord from Yusho patients

Jumboku Kajiwara, Takashi Todaka, Hironori Hirakawa, Tsuguhide Hori, Daisuke Yasutake, Reiko Nakagawa, Takao Iida, Junya Nagayama, Takesumi Yoshimura, Masutaka Furue

Research output: Contribution to journal › Article

Abstract

Dioxins are known as endocrine disrupters and widespread environmental contaminants. They are bioaccumulated in the human body. In this study, we determined concentrations of dioxins (PCDD, PCDF, Non-ortho PCB and Mono-ortho PCB) in eighteen umbilical cords provided by twelve mothers of Yusho patients and twelve umbilical cords provided by ten mothers of normal controls. The average concentrations of PCDD, PCDF, Non-ortho PCB, Mono-ortho PCB and total dioxins (PCDD/ F + Dioxin-like PCB) in the umbilical cords of Yusho patients and normal controls were 0.55, 4.55, 0.08, 0.08 and 5.26 pg-TEQ/g, respectively, and 0.50, 0.11, 0.03, 0.02 and 0.66 pg-TEQ/g, respectively. Total dioxins and PCDF concentrations in the umbilical cords of Yusho patient were about 8 and 40 times higher than those in the umbilical cords of normal controls, respectively. The average concentration of 2,3,4,7,8-PeCDF in the umbilical cords of Yusho patients was 10 pg/g. We couldn't detect 2,3,4,7, 8-PeCDF in the umbilical cords of normal controls. We suspected the 2,3,4,7,8-PeCDF concentrations in the mothers' blood were related to the 2,3,4,7,8-PeCDF concentrations in umbilical cords.

Original languageEnglish
Pages (from-to)179-182
Number of pages4
JournalFukuoka igaku zasshi = Hukuoka acta medica
Volume100
Issue number5
Publication statusPublished - Jan 1 2009
Externally publishedYes

Fingerprint

Dioxins
Umbilical Cord
Polychlorinated Biphenyls
Mothers
Human Body

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Dioxin concentration in the preserved umbilical cord from Yusho patients. / Kajiwara, Jumboku; Todaka, Takashi; Hirakawa, Hironori; Hori, Tsuguhide; Yasutake, Daisuke; Nakagawa, Reiko; Iida, Takao; Nagayama, Junya; Yoshimura, Takesumi; Furue, Masutaka.

In: Fukuoka igaku zasshi = Hukuoka acta medica, Vol. 100, No. 5, 01.01.2009, p. 179-182.

Research output: Contribution to journal › Article

Kajiwara, J, Todaka, T, Hirakawa, H, Hori, T, Yasutake, D, Nakagawa, R, Iida, T, Nagayama, J, Yoshimura, T & Furue, M 2009, 'Dioxin concentration in the preserved umbilical cord from Yusho patients', Fukuoka igaku zasshi = Hukuoka acta medica, vol. 100, no. 5, pp. 179-182.
Kajiwara J, Todaka T, Hirakawa H, Hori T, Yasutake D, Nakagawa R et al. Dioxin concentration in the preserved umbilical cord from Yusho patients. Fukuoka igaku zasshi = Hukuoka acta medica. 2009 Jan 1;100(5):179-182.
Kajiwara, Jumboku ; Todaka, Takashi ; Hirakawa, Hironori ; Hori, Tsuguhide ; Yasutake, Daisuke ; Nakagawa, Reiko ; Iida, Takao ; Nagayama, Junya ; Yoshimura, Takesumi ; Furue, Masutaka. / Dioxin concentration in the preserved umbilical cord from Yusho patients. In: Fukuoka igaku zasshi = Hukuoka acta medica. 2009 ; Vol. 100, No. 5. pp. 179-182.
@article{f394547181fc4c7a9ce189ea1b9bd87c,
title = "Dioxin concentration in the preserved umbilical cord from Yusho patients",
abstract = "Dioxins are known as endocrine disrupters and widespread environmental contaminants. They are bioaccumulated in the human body. In this study, we determined concentrations of dioxins (PCDD, PCDF, Non-ortho PCB and Mono-ortho PCB) in eighteen umbilical cords provided by twelve mothers of Yusho patients and twelve umbilical cords provided by ten mothers of normal controls. The average concentrations of PCDD, PCDF, Non-ortho PCB, Mono-ortho PCB and total dioxins (PCDD/ F + Dioxin-like PCB) in the umbilical cords of Yusho patients and normal controls were 0.55, 4.55, 0.08, 0.08 and 5.26 pg-TEQ/g, respectively, and 0.50, 0.11, 0.03, 0.02 and 0.66 pg-TEQ/g, respectively. Total dioxins and PCDF concentrations in the umbilical cords of Yusho patient were about 8 and 40 times higher than those in the umbilical cords of normal controls, respectively. The average concentration of 2,3,4,7,8-PeCDF in the umbilical cords of Yusho patients was 10 pg/g. We couldn't detect 2,3,4,7, 8-PeCDF in the umbilical cords of normal controls. We suspected the 2,3,4,7,8-PeCDF concentrations in the mothers' blood were related to the 2,3,4,7,8-PeCDF concentrations in umbilical cords.",
author = "Jumboku Kajiwara and Takashi Todaka and Hironori Hirakawa and Tsuguhide Hori and Daisuke Yasutake and Reiko Nakagawa and Takao Iida and Junya Nagayama and Takesumi Yoshimura and Masutaka Furue",
year = "2009",
month = "1",
day = "1",
language = "English",
volume = "100",
pages = "179--182",
journal = "Fukuoka Acta Medica",
issn = "0016-254X",
publisher = "福岡医学会",
number = "5",

}

TY - JOUR

T1 - Dioxin concentration in the preserved umbilical cord from Yusho patients

AU - Kajiwara, Jumboku

AU - Todaka, Takashi

AU - Hirakawa, Hironori

AU - Hori, Tsuguhide

AU - Yasutake, Daisuke

AU - Nakagawa, Reiko

AU - Iida, Takao

AU - Nagayama, Junya

AU - Yoshimura, Takesumi

AU - Furue, Masutaka

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Dioxins are known as endocrine disrupters and widespread environmental contaminants. They are bioaccumulated in the human body. In this study, we determined concentrations of dioxins (PCDD, PCDF, Non-ortho PCB and Mono-ortho PCB) in eighteen umbilical cords provided by twelve mothers of Yusho patients and twelve umbilical cords provided by ten mothers of normal controls. The average concentrations of PCDD, PCDF, Non-ortho PCB, Mono-ortho PCB and total dioxins (PCDD/ F + Dioxin-like PCB) in the umbilical cords of Yusho patients and normal controls were 0.55, 4.55, 0.08, 0.08 and 5.26 pg-TEQ/g, respectively, and 0.50, 0.11, 0.03, 0.02 and 0.66 pg-TEQ/g, respectively. Total dioxins and PCDF concentrations in the umbilical cords of Yusho patient were about 8 and 40 times higher than those in the umbilical cords of normal controls, respectively. The average concentration of 2,3,4,7,8-PeCDF in the umbilical cords of Yusho patients was 10 pg/g. We couldn't detect 2,3,4,7, 8-PeCDF in the umbilical cords of normal controls. We suspected the 2,3,4,7,8-PeCDF concentrations in the mothers' blood were related to the 2,3,4,7,8-PeCDF concentrations in umbilical cords.

AB - Dioxins are known as endocrine disrupters and widespread environmental contaminants. They are bioaccumulated in the human body. In this study, we determined concentrations of dioxins (PCDD, PCDF, Non-ortho PCB and Mono-ortho PCB) in eighteen umbilical cords provided by twelve mothers of Yusho patients and twelve umbilical cords provided by ten mothers of normal controls. The average concentrations of PCDD, PCDF, Non-ortho PCB, Mono-ortho PCB and total dioxins (PCDD/ F + Dioxin-like PCB) in the umbilical cords of Yusho patients and normal controls were 0.55, 4.55, 0.08, 0.08 and 5.26 pg-TEQ/g, respectively, and 0.50, 0.11, 0.03, 0.02 and 0.66 pg-TEQ/g, respectively. Total dioxins and PCDF concentrations in the umbilical cords of Yusho patient were about 8 and 40 times higher than those in the umbilical cords of normal controls, respectively. The average concentration of 2,3,4,7,8-PeCDF in the umbilical cords of Yusho patients was 10 pg/g. We couldn't detect 2,3,4,7, 8-PeCDF in the umbilical cords of normal controls. We suspected the 2,3,4,7,8-PeCDF concentrations in the mothers' blood were related to the 2,3,4,7,8-PeCDF concentrations in umbilical cords.

UR - http://www.scopus.com/inward/record.url?scp=68949118375&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=68949118375&partnerID=8YFLogxK

M3 - Article

C2 - 19588847

AN - SCOPUS:68949118375

VL - 100

SP - 179

EP - 182

JO - Fukuoka Acta Medica

JF - Fukuoka Acta Medica

SN - 0016-254X

IS - 5

ER -

Access to Document