Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices

Kentaro Fujiyoshi, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

This paper presents the development of a direct monitoring system of conformational transition from B- to A-DNA in microfluidics devices. Well-controlled laminar flows produced elongated large single DNA molecules onto chemically modified surfaces, and furthermore, ease of liquid-exchange operation of microfluidics devices enabled dynamic observation of B- to A-DNA conversion.

Original languageEnglish
Pages1396-1398
Number of pages3
Publication statusPublished - Jan 1 2006
Externally publishedYes
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: Nov 5 2006Nov 9 2006

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
CountryJapan
CityTokyo
Period11/5/0611/9/06

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Fujiyoshi, K., Kaji, N., Tokeshi, M., & Baba, Y. (2006). Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices. 1396-1398. Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.