Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices

Kentaro Fujiyoshi, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

This paper presents the development of a direct monitoring system of conformational transition from B- to A-DNA in microfluidics devices. Well-controlled laminar flows produced elongated large single DNA molecules onto chemically modified surfaces, and furthermore, ease of liquid-exchange operation of microfluidics devices enabled dynamic observation of B- to A-DNA conversion.

Original languageEnglish
Pages1396-1398
Number of pages3
Publication statusPublished - Jan 1 2006
Externally publishedYes
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: Nov 5 2006Nov 9 2006

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
CountryJapan
CityTokyo
Period11/5/0611/9/06

Fingerprint

A-Form DNA
Microfluidics
DNA
Ethanol
Molecules
Monitoring
Laminar flow
Liquids

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Fujiyoshi, K., Kaji, N., Tokeshi, M., & Baba, Y. (2006). Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices. 1396-1398. Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.

Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices. / Fujiyoshi, Kentaro; Kaji, Noritada; Tokeshi, Manabu; Baba, Yoshinobu.

2006. 1396-1398 Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.

Research output: Contribution to conferencePaper

Fujiyoshi, K, Kaji, N, Tokeshi, M & Baba, Y 2006, 'Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices' Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan, 11/5/06 - 11/9/06, pp. 1396-1398.
Fujiyoshi K, Kaji N, Tokeshi M, Baba Y. Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices. 2006. Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.
Fujiyoshi, Kentaro ; Kaji, Noritada ; Tokeshi, Manabu ; Baba, Yoshinobu. / Direct monitoring of B- to a-DNA conformational transition at a single molecule level induced by ethanol in microfluidic devices. Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.3 p.
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