Directional positive selection on an allele of arbitrary dominance

Kosuke M. Teshima, Molly Przeworski

Research output: Contribution to journalArticlepeer-review

56 Citations (Scopus)

Abstract

Most models of positive directional selection assume codominance of the beneficial allele. We examine the importance of this assumption by implementing a coalescent model of positive directional selection with arbitrary dominance. We find that, for a given mean fixation time, a beneficial allele has a much weaker effect on diversity at linked neutral sites when the allele is recessive.

Original languageEnglish
Pages (from-to)713-718
Number of pages6
JournalGenetics
Volume172
Issue number1
DOIs
Publication statusPublished - Jan 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics

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