Discrimination of D-amino acids from L-amino acids using electric potential changes of a membrane

H. Chibvongodze, Kenshi Hayashi, K. Toko

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Electric potential changes of optically active membranes due to different amino acid isomers were measured using a multichannel lipid membrane sensor. Because of the diastereomeric interaction between amino acids and the membrane, the membrane potential was determined by the optical activity of both the amino acid and the membrane. Diastereomeric interactions occur when an enantiomeric membrane resides in a chiral environment. The homochiral and heterochiral diastereomeric interactions differ sufficiently in the resultant arrangement of molecules at the surface of the membrane and permit the discrimination of D-amino acids from L-amino acids due to changes in the membrane characteristics.

Original languageEnglish
Pages (from-to)99-106
Number of pages8
JournalSensors and Materials
Volume13
Issue number2
Publication statusPublished - 2001

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Instrumentation

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