Discrimination of D-amino acids from L-amino acids using electric potential changes of a membrane

H. Chibvongodze, Kenshi Hayashi, K. Toko

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Electric potential changes of optically active membranes due to different amino acid isomers were measured using a multichannel lipid membrane sensor. Because of the diastereomeric interaction between amino acids and the membrane, the membrane potential was determined by the optical activity of both the amino acid and the membrane. Diastereomeric interactions occur when an enantiomeric membrane resides in a chiral environment. The homochiral and heterochiral diastereomeric interactions differ sufficiently in the resultant arrangement of molecules at the surface of the membrane and permit the discrimination of D-amino acids from L-amino acids due to changes in the membrane characteristics.

Original languageEnglish
Pages (from-to)99-106
Number of pages8
JournalSensors and Materials
Volume13
Issue number2
Publication statusPublished - 2001

Fingerprint

amino acids
discrimination
Amino acids
membranes
Membranes
Amino Acids
Electric potential
electric potential
Membrane Lipids
optical activity
Isomers
interactions
lipids
isomers
Molecules
Sensors
sensors
molecules

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Instrumentation

Cite this

Discrimination of D-amino acids from L-amino acids using electric potential changes of a membrane. / Chibvongodze, H.; Hayashi, Kenshi; Toko, K.

In: Sensors and Materials, Vol. 13, No. 2, 2001, p. 99-106.

Research output: Contribution to journalArticle

@article{14306567dc0a41639febefc0e2470d23,
title = "Discrimination of D-amino acids from L-amino acids using electric potential changes of a membrane",
abstract = "Electric potential changes of optically active membranes due to different amino acid isomers were measured using a multichannel lipid membrane sensor. Because of the diastereomeric interaction between amino acids and the membrane, the membrane potential was determined by the optical activity of both the amino acid and the membrane. Diastereomeric interactions occur when an enantiomeric membrane resides in a chiral environment. The homochiral and heterochiral diastereomeric interactions differ sufficiently in the resultant arrangement of molecules at the surface of the membrane and permit the discrimination of D-amino acids from L-amino acids due to changes in the membrane characteristics.",
author = "H. Chibvongodze and Kenshi Hayashi and K. Toko",
year = "2001",
language = "English",
volume = "13",
pages = "99--106",
journal = "Sensors and Materials",
issn = "0914-4935",
publisher = "M Y U Scientific Publishing Division",
number = "2",

}

TY - JOUR

T1 - Discrimination of D-amino acids from L-amino acids using electric potential changes of a membrane

AU - Chibvongodze, H.

AU - Hayashi, Kenshi

AU - Toko, K.

PY - 2001

Y1 - 2001

N2 - Electric potential changes of optically active membranes due to different amino acid isomers were measured using a multichannel lipid membrane sensor. Because of the diastereomeric interaction between amino acids and the membrane, the membrane potential was determined by the optical activity of both the amino acid and the membrane. Diastereomeric interactions occur when an enantiomeric membrane resides in a chiral environment. The homochiral and heterochiral diastereomeric interactions differ sufficiently in the resultant arrangement of molecules at the surface of the membrane and permit the discrimination of D-amino acids from L-amino acids due to changes in the membrane characteristics.

AB - Electric potential changes of optically active membranes due to different amino acid isomers were measured using a multichannel lipid membrane sensor. Because of the diastereomeric interaction between amino acids and the membrane, the membrane potential was determined by the optical activity of both the amino acid and the membrane. Diastereomeric interactions occur when an enantiomeric membrane resides in a chiral environment. The homochiral and heterochiral diastereomeric interactions differ sufficiently in the resultant arrangement of molecules at the surface of the membrane and permit the discrimination of D-amino acids from L-amino acids due to changes in the membrane characteristics.

UR - http://www.scopus.com/inward/record.url?scp=0035650302&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035650302&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0035650302

VL - 13

SP - 99

EP - 106

JO - Sensors and Materials

JF - Sensors and Materials

SN - 0914-4935

IS - 2

ER -