Distinct roles of microglia and monocytes in central nervous system inflammation and degeneration

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Monocytes and microglia both originate from myeloid precursor cells and share common characteristics even after differentiation. Recent studies have shown functional differences between these cell types, indicating their unique roles in lesion formation in neurodegenerative diseases. The present review summarizes the functional characteristics of these "similar but different" macrophages in both health and disease.

Original languageEnglish
Pages (from-to)41-48
Number of pages8
JournalClinical and Experimental Neuroimmunology
Volume5
Issue numbers1
DOIs
Publication statusPublished - Dec 1 2014

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Microglia
Myeloid Cells
Neurodegenerative Diseases
Monocytes
Central Nervous System
Macrophages
Inflammation
Health

All Science Journal Classification (ASJC) codes

  • Neuroscience (miscellaneous)
  • Immunology
  • Immunology and Microbiology (miscellaneous)
  • Clinical Neurology

Cite this

Distinct roles of microglia and monocytes in central nervous system inflammation and degeneration. / Yamasaki, Ryo.

In: Clinical and Experimental Neuroimmunology, Vol. 5, No. s1, 01.12.2014, p. 41-48.

Research output: Contribution to journalReview article

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