[Distributions and spreads of antimicrobial drug-resistant microorganisms in Saga prefecture].

Makiko Kiyosuke, Masaki Nagata, Zenzo Nagasawa, Yuzo Kayamori, Dongchon Kang, Hiroshi Miyamoto

Research output: Contribution to journalArticle

Abstract

We investigated the distribution of drug-resistant organisms to clarify transmission of the organisms. Drug-resistant organisms were surveyed in 12 facilities in 4 districts of Saga prefecture for 2 years, and were analyzed by beta-lactamase typing, antimicrobial susceptibility tests and pulsed-field gel electrophoresis (PFGE). The number of isolates was 111,505 for the 2 years. Questionnaires for drug-resistant organisms revealed that Methicillin-resistant Staphylococcus aureus (MRSA) was 64.1% of S. aureus, penicillin-intermediate Streptococcus pneumoniae (PISP) or penicillin-resistant S. pneumoniae (PRSP) 60.1% of S. pneumoniae, beta-lactamase-negative ampicillin-resistent Haemophilus inflluenzae (BLNAR) 19.4% of H. influenzae, Metallo-beta-Lactamase (MBL) 0.1% of gram-negative bacilli, multi-drug resistant Pseudomonas aeruginosa (MDRP) 0.6% of P. aeruginosa and extended-spectrum beta-lactamase (ESBL) producing organisms 8.0% and 3.1% of Escherichia coli and Klebsiella pneumoniae, respectively. PFGE analysis of ESBL E. coli revealed that 33 isolates collected from 7 facilities in 3 districts belonged to the same one group, indicating that this strain is transferred between different hospitals in different saga districts. Investigations of distribution of drug-resistant organisms in not only each hospitals but also in the first and the second medical areas are important for controls of healthcare-associated infections and antibiotic prescriptions.

Original languageEnglish
Pages (from-to)226-235
Number of pages10
JournalRinsho byori. The Japanese journal of clinical pathology
Volume59
Issue number3
Publication statusPublished - Mar 1 2011

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beta-Lactamases
Streptococcus pneumoniae
Pharmaceutical Preparations
Pulsed Field Gel Electrophoresis
Penicillins
Pseudomonas aeruginosa
Escherichia coli
Haemophilus
Klebsiella pneumoniae
Ampicillin
Methicillin-Resistant Staphylococcus aureus
Cross Infection
Bacillus
Human Influenza
Prescriptions
Staphylococcus aureus
Spectrum Analysis
Anti-Bacterial Agents

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

[Distributions and spreads of antimicrobial drug-resistant microorganisms in Saga prefecture]. / Kiyosuke, Makiko; Nagata, Masaki; Nagasawa, Zenzo; Kayamori, Yuzo; Kang, Dongchon; Miyamoto, Hiroshi.

In: Rinsho byori. The Japanese journal of clinical pathology, Vol. 59, No. 3, 01.03.2011, p. 226-235.

Research output: Contribution to journalArticle

Kiyosuke, Makiko ; Nagata, Masaki ; Nagasawa, Zenzo ; Kayamori, Yuzo ; Kang, Dongchon ; Miyamoto, Hiroshi. / [Distributions and spreads of antimicrobial drug-resistant microorganisms in Saga prefecture]. In: Rinsho byori. The Japanese journal of clinical pathology. 2011 ; Vol. 59, No. 3. pp. 226-235.
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