Diurnal variation in the response of the mandible to orthopedic force

S. Yamada, S. Saeki, Ichiro Takahashi, K. Igarashi, H. Shinoda, H. Mitani

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Abstract

Bone and cartilage metabolism is known to be more active during rest than during periods of activity. The purpose of this study was to examine the hypothesis that mandibular retractive force could be more effective when applied to rats during rest. Mandibular retractive force caused a considerable reduction in the condylar length in experimental groups, and the magnitude of this reduction was greater in the Light-period (08:00-20:00) group than in the Dark-period (20:00-08:00) group. The differentiation and proliferation of chondrocytes were inhibited in animals in the Light-period group, compared with those in the Dark-period group. These results suggest that the orthopedic effects of mandibular retractive force vary depending on the time of day the force is applied, and that such force may be more effective while animals are resting than while they are active.

Original languageEnglish
Pages (from-to)711-715
Number of pages5
JournalJournal of Dental Research
Volume81
Issue number10
DOIs
Publication statusPublished - Oct 1 2002
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Dentistry(all)

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