DNA ploidy is a major prognostic factor in advanced gastric carcinoma- univariate and multivariate analysis

M. Haraguchi; A. Watanabe; S. Moriguchi; D. Korenaga; Y. Maehara; T. Okamura; K. Sugimachi

DNA ploidy is a major prognostic factor in advanced gastric carcinoma- univariate and multivariate analysis

M. Haraguchi, A. Watanabe, S. Moriguchi, D. Korenaga, Y. Maehara, T. Okamura, K. Sugimachi

Surgery

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23 Citations (Scopus)

Abstract

DNA ploidy was determined by cytofluorometric analysis of paraffin- embedded malignant tissue from 96 Japanese patients in whom gastric carcinoma had invaded the serosa. Aneuploidy was found in gastric carcinoma tissue from 63 patients (66%). The postoperative 5-year survival rate of patients with aneuploid malignancy was significantly lower (13%) than those with diploid malignancy (36%) (p < 0.05). A multivariate analysis of various clinical and pathologic factors showed that tumor size, lymph node metastasis, vascular invasion, and DNA ploidy were significant and independent factors, which correlated with prognosis.

Original language	English
Pages (from-to)	814-819
Number of pages	6
Journal	Surgery
Volume	110
Issue number	5
Publication status	Published - Dec 1 1991

All Science Journal Classification (ASJC) codes

Surgery

Cite this

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abstract = "DNA ploidy was determined by cytofluorometric analysis of paraffin- embedded malignant tissue from 96 Japanese patients in whom gastric carcinoma had invaded the serosa. Aneuploidy was found in gastric carcinoma tissue from 63 patients (66%). The postoperative 5-year survival rate of patients with aneuploid malignancy was significantly lower (13%) than those with diploid malignancy (36%) (p < 0.05). A multivariate analysis of various clinical and pathologic factors showed that tumor size, lymph node metastasis, vascular invasion, and DNA ploidy were significant and independent factors, which correlated with prognosis.",

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T1 - DNA ploidy is a major prognostic factor in advanced gastric carcinoma- univariate and multivariate analysis

AU - Haraguchi, M.

AU - Watanabe, A.

AU - Moriguchi, S.

AU - Korenaga, D.

AU - Maehara, Y.

AU - Okamura, T.

AU - Sugimachi, K.

PY - 1991/12/1

Y1 - 1991/12/1

N2 - DNA ploidy was determined by cytofluorometric analysis of paraffin- embedded malignant tissue from 96 Japanese patients in whom gastric carcinoma had invaded the serosa. Aneuploidy was found in gastric carcinoma tissue from 63 patients (66%). The postoperative 5-year survival rate of patients with aneuploid malignancy was significantly lower (13%) than those with diploid malignancy (36%) (p < 0.05). A multivariate analysis of various clinical and pathologic factors showed that tumor size, lymph node metastasis, vascular invasion, and DNA ploidy were significant and independent factors, which correlated with prognosis.

AB - DNA ploidy was determined by cytofluorometric analysis of paraffin- embedded malignant tissue from 96 Japanese patients in whom gastric carcinoma had invaded the serosa. Aneuploidy was found in gastric carcinoma tissue from 63 patients (66%). The postoperative 5-year survival rate of patients with aneuploid malignancy was significantly lower (13%) than those with diploid malignancy (36%) (p < 0.05). A multivariate analysis of various clinical and pathologic factors showed that tumor size, lymph node metastasis, vascular invasion, and DNA ploidy were significant and independent factors, which correlated with prognosis.

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AN - SCOPUS:0026340862

SN - 0039-6060

VL - 110

SP - 814

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JO - Surgery

JF - Surgery

IS - 5

ER -

DNA ploidy is a major prognostic factor in advanced gastric carcinoma- univariate and multivariate analysis

Abstract

All Science Journal Classification (ASJC) codes

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