DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems

Shenliang Wang; Jia Guo; Toshikazu Ono; Eric T. Kool

doi:10.1002/anie.201201928

DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems

Shenliang Wang, Jia Guo, Toshikazu Ono, Eric T. Kool

Applied Chemistry

Research output: Contribution to journal › Article

24 Citations (Scopus)

Abstract

Dye-ing to live: Spectral limitations of common organic dyes make it difficult or impossible to visualize and follow multiple biological components in rapidly moving systems. The development of a multispectral set of improved DNA-scaffolded fluorophores is described. Their use in multicolor cellular imaging (see scheme) and in tracking of biological motions on the subsecond timescale is demonstrated.

Original language	English
Pages (from-to)	7176-7180
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	29
DOIs	https://doi.org/10.1002/anie.201201928
Publication status	Published - Jul 16 2012

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

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10.1002/anie.201201928

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Wang, S., Guo, J., Ono, T., & Kool, E. T. (2012). DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems. Angewandte Chemie - International Edition, 51(29), 7176-7180. https://doi.org/10.1002/anie.201201928

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