DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems

Shenliang Wang; Jia Guo; Toshikazu Ono; Eric T. Kool

doi:10.1002/anie.201201928

DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems

Shenliang Wang, Jia Guo, Toshikazu Ono, Eric T. Kool

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Dye-ing to live: Spectral limitations of common organic dyes make it difficult or impossible to visualize and follow multiple biological components in rapidly moving systems. The development of a multispectral set of improved DNA-scaffolded fluorophores is described. Their use in multicolor cellular imaging (see scheme) and in tracking of biological motions on the subsecond timescale is demonstrated.

Original language	English
Pages (from-to)	7176-7180
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	29
DOIs	https://doi.org/10.1002/anie.201201928
Publication status	Published - Jul 16 2012
Externally published	Yes

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

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10.1002/anie.201201928

Cite this

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abstract = "Dye-ing to live: Spectral limitations of common organic dyes make it difficult or impossible to visualize and follow multiple biological components in rapidly moving systems. The development of a multispectral set of improved DNA-scaffolded fluorophores is described. Their use in multicolor cellular imaging (see scheme) and in tracking of biological motions on the subsecond timescale is demonstrated.",

author = "Shenliang Wang and Jia Guo and Toshikazu Ono and Kool, {Eric T.}",

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AU - Guo, Jia

AU - Ono, Toshikazu

AU - Kool, Eric T.

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Y1 - 2012/7/16

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DNA polyfluorophores for real-time multicolor tracking of dynamic biological systems

Abstract

All Science Journal Classification (ASJC) codes

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