Does short-term cessation of smoking before lung resections reduce the risk of complications?

Tomoyoshi Takenaka, Fumihiro Shoji, Tetsuzo Tagawa, Fumihiko Kinoshita, Naoki Haratake, Makoto Edagawa, Koji Yamazaki, Mitsuhiro Takenoyama, Sadanori Takeo, Masaki Mori

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Smoking cessation is a highly important preparation before thoracic surgery. We examined the effects of short-term smoking cessation intervention before pulmonary resection on postoperative pulmonary complications (PPCs). Methods: A retrospective analysis of prospectively collected data was performed for 753 patients who underwent curative surgical resection for thoracic malignancy at 3 institutions. Patients with a smoking history were instructed to quit smoking. After confirming smoking cessation by at least four weeks before surgery, surgical resection was performed. Subjects were classified into three groups based on their smoking status: abstainers (anyone who had stopped smoking for at least 4 weeks but less than 2 months), former smokers (anyone who had abstained from smoking for more than two months prior to surgery), and never smokers (those who had never smoked). We examined the relationship between the preoperative smoking status and PPCs. Results: Surgery was performed for 660 primary lung cancers and 93 metastatic lung tumors. The smoking statuses were classified as follows: abstainers (n=105, 14%), former smokers (n=361; 48%) and never smokers (n=287, 38%). The incidence of PPCs among abstainers, former smokers and never smokers was 15%, 8% and 6%, respectively (P=0.01). The mean duration of post-operative chest tube drainage among abstainers, former smokers and never smokers was 3.2, 2.2 and 2.2 days, respectively (P=0.04). The mean post-operative hospital stay among abstainers, former smokers and never smokers was 12.1, 10.6 and 10.2 days, respectively (P=0.07). There was no 30-day mortality in the cohort. Conclusions: Short-term smoking cessation intervention did not enough reduce the PPCs as much as in former or never smokers.

Original languageEnglish
Pages (from-to)7127-7134
Number of pages8
JournalJournal of Thoracic Disease
Volume12
Issue number12
DOIs
Publication statusPublished - Dec 2020

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Fingerprint Dive into the research topics of 'Does short-term cessation of smoking before lung resections reduce the risk of complications?'. Together they form a unique fingerprint.

Cite this