Donor Age in Living Donor Liver Transplantation

T. Ikegami, A. Taketomi, R. Ohta, Y. Soejima, T. Yoshizumi, M. Shimada, Y. Maehara

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Background: We sought to elucidate the influence of donor age in living donor liver transplantation (LDLT) using either left lobe (LL) or right lobe (RL) grafts. Methods: Recipients (n = 232) were categorized as: group O/LL (LL, donor age >50, n = 20); group Y/LL (LL, donor age ≤50, n = 140); Group O/RL (RL, donor age >50, n = 12); and group Y/RL (RL, donor age ≤50, n = 61). We compared post-LDLT graft functions. Results: Among LL LDLT, the incidence of small-for-size syndrome was significantly greater for group O/LL compared with group Y/LL (60.0% vs 16.3%, P < .01). However, the cumulative 5-year graft survivals were 73.8% in group O and 76.7% in group Y without substantial difference. In RL LDLT, the post-LDLT morbidity and mortality were similar for group O/RL and group Y/RL. Conclusion: Partial liver grafts, even though LL grafts, from older donors can be used safely with caution in LDLT.

Original languageEnglish
Pages (from-to)1471-1475
Number of pages5
JournalTransplantation Proceedings
Volume40
Issue number5
DOIs
Publication statusPublished - Jun 2008

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

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