[Donor heart preservation with University of Wisconsin solution and immunosuppressive therapy with drip-infusion of tacrolimus].

Yoshihisa Tanoue, Ryuji Tominaga

Research output: Contribution to journalArticle

Abstract

Clinical approach for heart transplantation in Kyushu University Hospital Heart Center about donor heart preservation and immunosuppressive therapy is reviewed. University of Wisconsin solution has been used for donor heart preservation as the 1st-line solution, because left ventricular function after both 6-hour and 24-hour preservation with University of Wisconsin solution was superior to that with Celsior solution on the cross-circulated rabbit heart preparation model. Donor hearts are arrested by the extracellular-type cardioplegia to prevent coronary vasoconstriction associated with preservation in University of Wisconsin solution. Tacrolimus has been used as immunosuppressive agent. Drip-infusion of tacrolimus (0.02 mg/kg per day) is started immediately after heart transplantation aiming at definitive blood level control.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalUnknown Journal
Volume66
Issue number1
Publication statusPublished - Jan 1 2013

Fingerprint

Tacrolimus
Immunosuppressive Agents
Intravenous Infusions
Heart Transplantation
Therapeutics
Induced Heart Arrest
Vasoconstriction
Left Ventricular Function
Rabbits

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

[Donor heart preservation with University of Wisconsin solution and immunosuppressive therapy with drip-infusion of tacrolimus]. / Tanoue, Yoshihisa; Tominaga, Ryuji.

In: Unknown Journal, Vol. 66, No. 1, 01.01.2013, p. 37-41.

Research output: Contribution to journalArticle

@article{e1942bc830df49f99cfbb5c888ce4866,
title = "[Donor heart preservation with University of Wisconsin solution and immunosuppressive therapy with drip-infusion of tacrolimus].",
abstract = "Clinical approach for heart transplantation in Kyushu University Hospital Heart Center about donor heart preservation and immunosuppressive therapy is reviewed. University of Wisconsin solution has been used for donor heart preservation as the 1st-line solution, because left ventricular function after both 6-hour and 24-hour preservation with University of Wisconsin solution was superior to that with Celsior solution on the cross-circulated rabbit heart preparation model. Donor hearts are arrested by the extracellular-type cardioplegia to prevent coronary vasoconstriction associated with preservation in University of Wisconsin solution. Tacrolimus has been used as immunosuppressive agent. Drip-infusion of tacrolimus (0.02 mg/kg per day) is started immediately after heart transplantation aiming at definitive blood level control.",
author = "Yoshihisa Tanoue and Ryuji Tominaga",
year = "2013",
month = "1",
day = "1",
language = "English",
volume = "66",
pages = "37--41",
journal = "Quaternary International",
issn = "1040-6182",
publisher = "Elsevier Limited",
number = "1",

}

TY - JOUR

T1 - [Donor heart preservation with University of Wisconsin solution and immunosuppressive therapy with drip-infusion of tacrolimus].

AU - Tanoue, Yoshihisa

AU - Tominaga, Ryuji

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Clinical approach for heart transplantation in Kyushu University Hospital Heart Center about donor heart preservation and immunosuppressive therapy is reviewed. University of Wisconsin solution has been used for donor heart preservation as the 1st-line solution, because left ventricular function after both 6-hour and 24-hour preservation with University of Wisconsin solution was superior to that with Celsior solution on the cross-circulated rabbit heart preparation model. Donor hearts are arrested by the extracellular-type cardioplegia to prevent coronary vasoconstriction associated with preservation in University of Wisconsin solution. Tacrolimus has been used as immunosuppressive agent. Drip-infusion of tacrolimus (0.02 mg/kg per day) is started immediately after heart transplantation aiming at definitive blood level control.

AB - Clinical approach for heart transplantation in Kyushu University Hospital Heart Center about donor heart preservation and immunosuppressive therapy is reviewed. University of Wisconsin solution has been used for donor heart preservation as the 1st-line solution, because left ventricular function after both 6-hour and 24-hour preservation with University of Wisconsin solution was superior to that with Celsior solution on the cross-circulated rabbit heart preparation model. Donor hearts are arrested by the extracellular-type cardioplegia to prevent coronary vasoconstriction associated with preservation in University of Wisconsin solution. Tacrolimus has been used as immunosuppressive agent. Drip-infusion of tacrolimus (0.02 mg/kg per day) is started immediately after heart transplantation aiming at definitive blood level control.

UR - http://www.scopus.com/inward/record.url?scp=84885576900&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885576900&partnerID=8YFLogxK

M3 - Article

C2 - 23985403

AN - SCOPUS:84885576900

VL - 66

SP - 37

EP - 41

JO - Quaternary International

JF - Quaternary International

SN - 1040-6182

IS - 1

ER -