Doppler spectral waveform analysis of arteries of the hand in patients with Raynaud's phenomenon as compared with healthy subjects

Toru Chikui, Masahiro Izumi, Katsumi Eguchi, Yojiro Kawabe, Takashi Nakamura

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

OBJECTIVE. We sought to characterize and compare the blood flow patterns of peripheral arteries of the hand in patients with Raynaud's phenomenon and in healthy subjects. SUBJECTS AND METHODS. We used Doppler sonography to assess the blood flow pattern of the proper palmar digital artery and the deep radial arch in the hands of 79 healthy subjects and 24 patients with primary and secondary Raynaud's phenomenon. We determined the resistive index, pulsatility index, peak systolic velocity, and end-diastolic velocity of these peripheral arteries at rest and after cold immersion. RESULTS. The proper palmar digital artery of healthy subjects showed higher end-diastolic velocities and lower resistive indexes than did the deep radial arch. Compared with healthy subjects, patients with Raynaud's phenomenon had higher resistive and pulsatility indexes but lower peak systolic and end-diastolic velocities in these arteries. Accordingly, the differences in end-diastolic velocity and resistive index seen in the two peripheral arteries of healthy subjects were not seen in patients with Raynaud's phenomenon. Analysis of receiver operating characteristic curves showed high diagnostic accuracy in detecting the disease. Cold-immersion studies revealed that for the proper palmar digital arteries throughout the time after immersion, all these Doppler parameters were significantly lower for the velocities and higher for the indexes in patients with Raynaud's phenomenon than in healthy subjects. CONCLUSION. Taken together, these results suggest a legitimate role for Doppler sonography in the assessment of Raynaud's phenomenon.

Original languageEnglish
Pages (from-to)1605-1609
Number of pages5
JournalAmerican Journal of Roentgenology
Volume172
Issue number6
DOIs
Publication statusPublished - Jan 1 1999
Externally publishedYes

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Raynaud Disease
Healthy Volunteers
Hand
Arteries
Immersion
Doppler Ultrasonography
Radial Artery
ROC Curve

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Doppler spectral waveform analysis of arteries of the hand in patients with Raynaud's phenomenon as compared with healthy subjects. / Chikui, Toru; Izumi, Masahiro; Eguchi, Katsumi; Kawabe, Yojiro; Nakamura, Takashi.

In: American Journal of Roentgenology, Vol. 172, No. 6, 01.01.1999, p. 1605-1609.

Research output: Contribution to journalArticle

Chikui, Toru ; Izumi, Masahiro ; Eguchi, Katsumi ; Kawabe, Yojiro ; Nakamura, Takashi. / Doppler spectral waveform analysis of arteries of the hand in patients with Raynaud's phenomenon as compared with healthy subjects. In: American Journal of Roentgenology. 1999 ; Vol. 172, No. 6. pp. 1605-1609.
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