Doppler velocimetry in the adrenal artery in human fetuses

Yasuyuki Fujita, Shoji Satoh, Hitoo Nakano

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Fetal hypoxia and/or acidosis causes redistribution of blood flow to the high-priority organs including the adrenal glands. Although this phenomenon is well described in the human cerebral and placental circulations using Doppler velocimetry, there are few reports about the adrenal glands. Aim: To clarify the gestational age-related changes in adrenal blood flow in normal fetuses and fetuses at risk of hemodynamic derangement. Material and Methods: In 153 normal cases, the resistance indices (RIs) calculated from the blood flow velocity waveforms (FVWs) in the middle adrenal artery (MAA) were obtained from 24 weeks to construct nomogram using regression analysis. Twenty-seven complicated cases were divided according to the 5%ile RI values in the MAA, and clinical outcomes were retrospectively compared. Result: The RI values in the MAA increased until 31 weeks and decreased thereafter. The 50%ile regression curve was represented as RI=-0.000914 (weeks)2+0.0579 weeks-0.181. Of the 27 complicated cases, 13 had RIs in the MAA below the 5%ile. Cases with low RI had significantly higher RI ratio in regard of UA/MCA; higher occurrence of abnormal FHR patterns on observation; higher incidence of cesarean delivery for nonreassuring fetal well-being status; earlier gestational age at delivery; lower birth weights and longer periods of admission to NICU than the cases with normal RI. Conclusion: We have described the nomogram for the RI in the MAA. In conditions of fetal hypoxia or acidemia, blood flow redistribution to the adrenal glands may occur and the analysis of the adrenal artery FVWs may be useful in detection of fetal altered hemodynamics.

Original languageEnglish
Pages (from-to)47-55
Number of pages9
JournalEarly Human Development
Volume65
Issue number1
DOIs
Publication statusPublished - Aug 23 2001

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Rheology
Fetus
Arteries
Adrenal Glands
Fetal Hypoxia
Nomograms
Gestational Age
Cerebrovascular Circulation
Hemodynamics
Placental Circulation
Blood Flow Velocity
Acidosis
Birth Weight
Regression Analysis
Observation
Incidence

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

Doppler velocimetry in the adrenal artery in human fetuses. / Fujita, Yasuyuki; Satoh, Shoji; Nakano, Hitoo.

In: Early Human Development, Vol. 65, No. 1, 23.08.2001, p. 47-55.

Research output: Contribution to journalArticle

Fujita, Yasuyuki ; Satoh, Shoji ; Nakano, Hitoo. / Doppler velocimetry in the adrenal artery in human fetuses. In: Early Human Development. 2001 ; Vol. 65, No. 1. pp. 47-55.
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