Dual pH-triggered multistage drug delivery systems based on host–guest interaction-associated polymeric nanogels

Minghui Zan, Junjie Li, Shizhong Luo, Zhishen Ge

Research output: Contribution to journalArticlepeer-review

83 Citations (Scopus)

Abstract

The polymeric nanogels were constructed via host–guest interactions for dual pH-triggered multistage drug delivery, which showed tumor acidity-triggered nanogel reorganization into smaller nanoparticles for deep tissue penetration, high-efficiency cellular uptake, and intracellular endo-lysosomal pH-responsive drug release.

Original languageEnglish
Pages (from-to)7824-7827
Number of pages4
JournalChemical Communications
Volume50
Issue number58
DOIs
Publication statusPublished - Jun 24 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Dual pH-triggered multistage drug delivery systems based on host–guest interaction-associated polymeric nanogels'. Together they form a unique fingerprint.

Cite this