Abstract
It has been found that (E)-5-cyclononen-1-one (2a) exhibits marginal planar chirality owing to an insufficient topological constraint, whereas the enolates 3 derived from 2a show robust planar chirality. Enantioenriched enolates are easily prepared by enzymatic hydrolysis, and they show an ability to serve as chiral nucleophiles.
Original language | English |
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Pages (from-to) | 1754-1756 |
Number of pages | 3 |
Journal | Journal of the American Chemical Society |
Volume | 133 |
Issue number | 6 |
DOIs | |
Publication status | Published - Feb 16 2011 |
All Science Journal Classification (ASJC) codes
- Catalysis
- Chemistry(all)
- Biochemistry
- Colloid and Surface Chemistry