Dynamic flow imaging using 320-detector row CT and motion coherence analysis in coronary aneurysms associated with Kawasaki disease

Yamato Shimomiya, Michinobu Nagao, Yuzo Yamasaki, Takashi Shirasaka, Masatoshi Kondo, Tsukasa Kojima, Akihiro Nishie, Kenichiro Yamamura, Hiroshi Honda

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Introduction We propose a new dynamic flow imaging using 320-detector row CT, and investigate the assessment of coronary flow in aneurysms of Kawasaki disease in adulthood. Methods Six patients with Kawasaki disease and coronary aneurysms associated (26.7 years old) and six controls were enrolled. Dynamic coronary CT angiography with 320-row CT was continuously performed at mid-diastole throughout 15-25 cardiac cycles with prospective Electrocardiogram gating after injection of contrast media. Dynamic data sets of 15-25 cycles were computed into 90-100 data sets by motion coherence image processing. Next, time-density curves for coronary arteries were calculated for all the phases. On the basis of the maximum slope method, coronary flow index was defined as the ratio of the maximum upslope of the attenuation of coronary arteries to the upslope of the attenuation of ascending aorta on the time-density curves. Coronary flow indexes for the proximal and distal sites of coronary arteries and intra-aneurysm were measured.

Original languageEnglish
Pages (from-to)416-420
Number of pages5
JournalCardiology in the Young
Volume28
Issue number3
DOIs
Publication statusPublished - Mar 1 2018

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

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