Dynamic interfacial properties of polyethylene glycol-modified ferritin at the solid/liquid interface

Yoshikazu Kumashiro, Yasuhiro Ikezoe, Kaoru Tamada, Masahiko Hara

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Poly(ethylene glycol)-modified ferritins (PEG-ferritins) with various molecular weights were synthesized by the grafting method, and their dynamic interfacial properties at the solid/liquid interface were investigated. The number of PEG grafted to ferritins was controlled by the amount of 1,1′-carbonyldiimidazole-modified PEG adding to the reaction solution. The adsorption kinetics and energy dissipation of PEG-ferritins onto bare Si substrate and amino-modified Si substrate were investigated with a quartz crystal microbalance (QCM) in 10 mM bis-Tris/HCl buffer (pH 5.8), while their morphologies were characterized by scanning electron microscopy (SEM). The adsorption dynamics of PEG-ferritins onto amino-modified Si substrate were quite different from those of unmodified ferritin, which can be reasonably interpreted by the desorption capability of PEG-ferritins on the surface attributed to amphiphilicity and the high-chain mobility of PEG chains.

Original languageEnglish
Pages (from-to)8291-8297
Number of pages7
JournalJournal of Physical Chemistry B
Volume112
Issue number28
DOIs
Publication statusPublished - Jul 17 2008

Fingerprint

liquid-solid interfaces
Ferritins
Polyethylene glycols
glycols
polyethylenes
ethylene
Ethylene Glycol
Liquids
Adsorption
adsorption
quartz crystals
Quartz Crystal Microbalance Techniques
microbalances
Substrates
molecular weight
Tromethamine
dissipation
buffers
energy dissipation
desorption

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films
  • Materials Chemistry

Cite this

Dynamic interfacial properties of polyethylene glycol-modified ferritin at the solid/liquid interface. / Kumashiro, Yoshikazu; Ikezoe, Yasuhiro; Tamada, Kaoru; Hara, Masahiko.

In: Journal of Physical Chemistry B, Vol. 112, No. 28, 17.07.2008, p. 8291-8297.

Research output: Contribution to journalArticle

Kumashiro, Yoshikazu ; Ikezoe, Yasuhiro ; Tamada, Kaoru ; Hara, Masahiko. / Dynamic interfacial properties of polyethylene glycol-modified ferritin at the solid/liquid interface. In: Journal of Physical Chemistry B. 2008 ; Vol. 112, No. 28. pp. 8291-8297.
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