Dynamics in the folding of long DNA chain under strong flow

Takuya Saito, Takahiro Sakaue, Daiji Kaneko, Masao Washizu, Hidehiro Oana

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper presents the study about the dynamics in the folding of long DNA under strong flow. Di- rect observation of the folding process of the tethered DNA molecule induced by adding a condensing agent is demonstrated using a microfluidic device, and this theoretical interpretation of the process is provided. From the direct observation, it is found that the fold- ing dynamics typically exhibits characteristic three stages: (i) initial rapid compaction, (ii) slowing-down, (iii) sudden speed-up. Such a notable feature pin- points a nonequilibrium flow effect and can be inter- preted by a simple theory, which takes account of the nonuniformity of the tethered chain stretched by flow.

Original languageEnglish
Title of host publication2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics"
Pages118-123
Number of pages6
DOIs
Publication statusPublished - Dec 1 2008
Event2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation" - Nagoya, Japan
Duration: Nov 6 2008Nov 9 2008

Publication series

Name2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008

Other

Other2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation"
CountryJapan
CityNagoya
Period11/6/0811/9/08

Fingerprint

DNA
Microfluidics
Compaction
Molecules

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition
  • Human-Computer Interaction
  • Electrical and Electronic Engineering

Cite this

Saito, T., Sakaue, T., Kaneko, D., Washizu, M., & Oana, H. (2008). Dynamics in the folding of long DNA chain under strong flow. In 2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics" (pp. 118-123). [4752434] (2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008). https://doi.org/10.1109/MHS.2008.4752434

Dynamics in the folding of long DNA chain under strong flow. / Saito, Takuya; Sakaue, Takahiro; Kaneko, Daiji; Washizu, Masao; Oana, Hidehiro.

2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics". 2008. p. 118-123 4752434 (2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Saito, T, Sakaue, T, Kaneko, D, Washizu, M & Oana, H 2008, Dynamics in the folding of long DNA chain under strong flow. in 2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics"., 4752434, 2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, pp. 118-123, 2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation", Nagoya, Japan, 11/6/08. https://doi.org/10.1109/MHS.2008.4752434
Saito T, Sakaue T, Kaneko D, Washizu M, Oana H. Dynamics in the folding of long DNA chain under strong flow. In 2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics". 2008. p. 118-123. 4752434. (2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008). https://doi.org/10.1109/MHS.2008.4752434
Saito, Takuya ; Sakaue, Takahiro ; Kaneko, Daiji ; Washizu, Masao ; Oana, Hidehiro. / Dynamics in the folding of long DNA chain under strong flow. 2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics". 2008. pp. 118-123 (2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008).
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