Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma

Toshihiro Mlyamoto; Hsashi Gondo; Yasushi Mlyoshi; Hrokazu Snigematsu; Toshio Mlnematsu; Katsuto Takenaka; Kazuki Tanimoio; Takahiko Horiucm; Yoshinobu Asano; Shoichi Inaba; Yoichi Minamishima; Yosniyuki Niho

doi:10.1046/j.1365-2141.1998.00572.x

Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma

Toshihiro Mlyamoto, Hsashi Gondo, Yasushi Mlyoshi, Hrokazu Snigematsu, Toshio Mlnematsu, Katsuto Takenaka, Kazuki Tanimoio, Takahiko Horiucm, Yoshinobu Asano, Shoichi Inaba, Yoichi Minamishima, Yosniyuki Niho

Hematology, Oncology & Cardiovascular medicine

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

A patient with non-Hodgkin's lymphoma who received a CD34-selected autologous peripheral blood stem cell transplant (PBSCT) developed cytomegalovirus retinitis, adenovirus-associated haemorrhagic cystitis (HC) and fatal herpes simplex virus pneumonia. Depletion of mature T cells from the graft and a persistent decrease in CD4⁺ lymphocytes following PBSCT may have predisposed this patient to such viral infections. Infusion of cryopreserved autologous PBSC (containing mature T cells) was effective for adenovirus-associated HC. Immunosuppression and resultant vital infections may affect patients receiving CD34-selected autologous transplantation.

Original language	English
Pages (from-to)	348-350
Number of pages	3
Journal	British Journal of Haematology
Volume	100
Issue number	2
DOIs	https://doi.org/10.1046/j.1365-2141.1998.00572.x
Publication status	Published - 1998

All Science Journal Classification (ASJC) codes

Hematology

Access to Document

10.1046/j.1365-2141.1998.00572.x

Cite this

Mlyamoto, T., Gondo, H., Mlyoshi, Y., Snigematsu, H., Mlnematsu, T., Takenaka, K., Tanimoio, K., Horiucm, T., Asano, Y., Inaba, S., Minamishima, Y., & Niho, Y. (1998). Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma. British Journal of Haematology, 100(2), 348-350. https://doi.org/10.1046/j.1365-2141.1998.00572.x

Mlyamoto, T, Gondo, H, Mlyoshi, Y, Snigematsu, H, Mlnematsu, T, Takenaka, K, Tanimoio, K, Horiucm, T, Asano, Y, Inaba, S, Minamishima, Y & Niho, Y 1998, 'Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma', British Journal of Haematology, vol. 100, no. 2, pp. 348-350. https://doi.org/10.1046/j.1365-2141.1998.00572.x

@article{64f78d8e9d474bdc9bf9905071d2b8b7,

title = "Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma",

abstract = "A patient with non-Hodgkin's lymphoma who received a CD34-selected autologous peripheral blood stem cell transplant (PBSCT) developed cytomegalovirus retinitis, adenovirus-associated haemorrhagic cystitis (HC) and fatal herpes simplex virus pneumonia. Depletion of mature T cells from the graft and a persistent decrease in CD4+ lymphocytes following PBSCT may have predisposed this patient to such viral infections. Infusion of cryopreserved autologous PBSC (containing mature T cells) was effective for adenovirus-associated HC. Immunosuppression and resultant vital infections may affect patients receiving CD34-selected autologous transplantation.",

author = "Toshihiro Mlyamoto and Hsashi Gondo and Yasushi Mlyoshi and Hrokazu Snigematsu and Toshio Mlnematsu and Katsuto Takenaka and Kazuki Tanimoio and Takahiko Horiucm and Yoshinobu Asano and Shoichi Inaba and Yoichi Minamishima and Yosniyuki Niho",

year = "1998",

doi = "10.1046/j.1365-2141.1998.00572.x",

language = "English",

volume = "100",

pages = "348--350",

journal = "British Journal of Haematology",

issn = "0007-1048",

publisher = "Wiley-Blackwell",

number = "2",

}

TY - JOUR

T1 - Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma

AU - Mlyamoto, Toshihiro

AU - Gondo, Hsashi

AU - Mlyoshi, Yasushi

AU - Snigematsu, Hrokazu

AU - Mlnematsu, Toshio

AU - Takenaka, Katsuto

AU - Tanimoio, Kazuki

AU - Horiucm, Takahiko

AU - Asano, Yoshinobu

AU - Inaba, Shoichi

AU - Minamishima, Yoichi

AU - Niho, Yosniyuki

PY - 1998

Y1 - 1998

N2 - A patient with non-Hodgkin's lymphoma who received a CD34-selected autologous peripheral blood stem cell transplant (PBSCT) developed cytomegalovirus retinitis, adenovirus-associated haemorrhagic cystitis (HC) and fatal herpes simplex virus pneumonia. Depletion of mature T cells from the graft and a persistent decrease in CD4+ lymphocytes following PBSCT may have predisposed this patient to such viral infections. Infusion of cryopreserved autologous PBSC (containing mature T cells) was effective for adenovirus-associated HC. Immunosuppression and resultant vital infections may affect patients receiving CD34-selected autologous transplantation.

AB - A patient with non-Hodgkin's lymphoma who received a CD34-selected autologous peripheral blood stem cell transplant (PBSCT) developed cytomegalovirus retinitis, adenovirus-associated haemorrhagic cystitis (HC) and fatal herpes simplex virus pneumonia. Depletion of mature T cells from the graft and a persistent decrease in CD4+ lymphocytes following PBSCT may have predisposed this patient to such viral infections. Infusion of cryopreserved autologous PBSC (containing mature T cells) was effective for adenovirus-associated HC. Immunosuppression and resultant vital infections may affect patients receiving CD34-selected autologous transplantation.

UR - http://www.scopus.com/inward/record.url?scp=6844240194&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=6844240194&partnerID=8YFLogxK

U2 - 10.1046/j.1365-2141.1998.00572.x

DO - 10.1046/j.1365-2141.1998.00572.x

M3 - Article

C2 - 9488625

AN - SCOPUS:6844240194

SN - 0007-1048

VL - 100

SP - 348

EP - 350

JO - British Journal of Haematology

JF - British Journal of Haematology

IS - 2

ER -

Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this