Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma

Toshihiro Mlyamoto, Hsashi Gondo, Yasushi Mlyoshi, Hrokazu Snigematsu, Toshio Mlnematsu, Katsuto Takenaka, Kazuki Tanimoio, Takahiko Horiucm, Yoshinobu Asano, Shoichi Inaba, Yoichi Minamishima, Yosniyuki Niho

Research output: Contribution to journalArticle

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Abstract

A patient with non-Hodgkin's lymphoma who received a CD34-selected autologous peripheral blood stem cell transplant (PBSCT) developed cytomegalovirus retinitis, adenovirus-associated haemorrhagic cystitis (HC) and fatal herpes simplex virus pneumonia. Depletion of mature T cells from the graft and a persistent decrease in CD4+ lymphocytes following PBSCT may have predisposed this patient to such viral infections. Infusion of cryopreserved autologous PBSC (containing mature T cells) was effective for adenovirus-associated HC. Immunosuppression and resultant vital infections may affect patients receiving CD34-selected autologous transplantation.

Original languageEnglish
Pages (from-to)348-350
Number of pages3
JournalBritish Journal of Haematology
Volume100
Issue number2
DOIs
Publication statusPublished - Apr 2 1998

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Peripheral Blood Stem Cell Transplantation
Non-Hodgkin's Lymphoma
Cystitis
Transplants
Adenoviridae
Cytomegalovirus Retinitis
T-Lymphocytes
Autologous Transplantation
Virus Diseases
Simplexvirus
Immunosuppression
Pneumonia
Lymphocytes
Infection
Peripheral Blood Stem Cells

All Science Journal Classification (ASJC) codes

  • Hematology

Cite this

Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma. / Mlyamoto, Toshihiro; Gondo, Hsashi; Mlyoshi, Yasushi; Snigematsu, Hrokazu; Mlnematsu, Toshio; Takenaka, Katsuto; Tanimoio, Kazuki; Horiucm, Takahiko; Asano, Yoshinobu; Inaba, Shoichi; Minamishima, Yoichi; Niho, Yosniyuki.

In: British Journal of Haematology, Vol. 100, No. 2, 02.04.1998, p. 348-350.

Research output: Contribution to journalArticle

Mlyamoto, T, Gondo, H, Mlyoshi, Y, Snigematsu, H, Mlnematsu, T, Takenaka, K, Tanimoio, K, Horiucm, T, Asano, Y, Inaba, S, Minamishima, Y & Niho, Y 1998, 'Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma', British Journal of Haematology, vol. 100, no. 2, pp. 348-350. https://doi.org/10.1046/j.1365-2141.1998.00572.x
Mlyamoto, Toshihiro ; Gondo, Hsashi ; Mlyoshi, Yasushi ; Snigematsu, Hrokazu ; Mlnematsu, Toshio ; Takenaka, Katsuto ; Tanimoio, Kazuki ; Horiucm, Takahiko ; Asano, Yoshinobu ; Inaba, Shoichi ; Minamishima, Yoichi ; Niho, Yosniyuki. / Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma. In: British Journal of Haematology. 1998 ; Vol. 100, No. 2. pp. 348-350.
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