A strong earthquake can cause a large number of landslides and avalanches, which can initiate causal geo-disaster chains. A representative ring in disaster chain is that a coseismic landslide can block a river and form a landslide dam, which may burst and cause a catastrophic flood. In order to disclose the serious impacts of the geo-disaster chain induced by earthquake, this paper presented the form process of geo-disaster chain and proposed some cutting measures. According to the developing process, the geo-disaster chain from the 2008 Wenchuan earthquake was discussed. Two measures for cutting the chain are proposed, one is the landslide hazard map constructing on susceptibility analysis and the other is numerical simulation of debris flows for assessment of dangerous zone. The results of this study can help the authority make the right decision rapidly to take appropriate counter measures to reduce the risk of the geo-disaster chain or cut it directly.