Abstract
Background/purpose The purpose of this study was to investigate echocardiographic parameters in relation to the outcomes of isolated left-sided congenital diaphragmatic hernia (CDH). Methods This multicenter, retrospective, observational study was conducted among patients with CDH born between 2006 and 2010. Patients in this study did not have severe cardiac malformations or chromosomal aberrations. Patients with incomplete echocardiographic examinations were excluded. In total, 84 patients with left-sided isolated CDH were included in this study. The prognostic parameters were obtained from postnatal echocardiographic images within 24 h after birth. Results Eight patients died before 90 days of birth. Univariate analysis showed that the presence of continuous right to left shunt at the ductus, left pulmonary artery diameter of < 2.7 mm, right pulmonary artery diameter of < 3.3 mm, and left ventricular diastolic diameter of < 10.8 mm, were the predictors of poor prognosis. Multivariate logistic regression analysis showed that right pulmonary artery diameter of < 3.3 mm (adjusted OR 10.28, 95% C.I.: 1.15–249.19) and left ventricular diastolic diameter of < 10.8 mm (adjusted OR 7.86, 95% C.I.: 1.01–82.82) were predictors of poor prognosis. Conclusions This study revealed that the predictors of poor prognosis associated with CDH include smaller right pulmonary artery and left ventricular diastolic diameters. Retrospective Study-Level II.
| Original language | English |
|---|---|
| Pages (from-to) | 1926-1930 |
| Number of pages | 5 |
| Journal | Journal of Pediatric Surgery |
| Volume | 51 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 1 2016 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Pediatrics, Perinatology, and Child Health
Cite this
Echocardiographic predictors of poor prognosis in congenital diaphragmatic hernia. / Yamoto, Masaya; Inamura, Noboru; Terui, Keita; Nagata, Kouji; Kanamori, Yutaka; Hayakawa, Masahiro; Tazuke, Yuko; Yokoi, Akiko; Takayasu, Hajime; Okuyama, Hiroomi; Fukumoto, Koji; Urushihara, Naoto; Taguchi, Tomoaki; Usui, Noriaki.
In: Journal of Pediatric Surgery, Vol. 51, No. 12, 01.12.2016, p. 1926-1930.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Echocardiographic predictors of poor prognosis in congenital diaphragmatic hernia
AU - Yamoto, Masaya
AU - Inamura, Noboru
AU - Terui, Keita
AU - Nagata, Kouji
AU - Kanamori, Yutaka
AU - Hayakawa, Masahiro
AU - Tazuke, Yuko
AU - Yokoi, Akiko
AU - Takayasu, Hajime
AU - Okuyama, Hiroomi
AU - Fukumoto, Koji
AU - Urushihara, Naoto
AU - Taguchi, Tomoaki
AU - Usui, Noriaki
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Background/purpose The purpose of this study was to investigate echocardiographic parameters in relation to the outcomes of isolated left-sided congenital diaphragmatic hernia (CDH). Methods This multicenter, retrospective, observational study was conducted among patients with CDH born between 2006 and 2010. Patients in this study did not have severe cardiac malformations or chromosomal aberrations. Patients with incomplete echocardiographic examinations were excluded. In total, 84 patients with left-sided isolated CDH were included in this study. The prognostic parameters were obtained from postnatal echocardiographic images within 24 h after birth. Results Eight patients died before 90 days of birth. Univariate analysis showed that the presence of continuous right to left shunt at the ductus, left pulmonary artery diameter of < 2.7 mm, right pulmonary artery diameter of < 3.3 mm, and left ventricular diastolic diameter of < 10.8 mm, were the predictors of poor prognosis. Multivariate logistic regression analysis showed that right pulmonary artery diameter of < 3.3 mm (adjusted OR 10.28, 95% C.I.: 1.15–249.19) and left ventricular diastolic diameter of < 10.8 mm (adjusted OR 7.86, 95% C.I.: 1.01–82.82) were predictors of poor prognosis. Conclusions This study revealed that the predictors of poor prognosis associated with CDH include smaller right pulmonary artery and left ventricular diastolic diameters. Retrospective Study-Level II.
AB - Background/purpose The purpose of this study was to investigate echocardiographic parameters in relation to the outcomes of isolated left-sided congenital diaphragmatic hernia (CDH). Methods This multicenter, retrospective, observational study was conducted among patients with CDH born between 2006 and 2010. Patients in this study did not have severe cardiac malformations or chromosomal aberrations. Patients with incomplete echocardiographic examinations were excluded. In total, 84 patients with left-sided isolated CDH were included in this study. The prognostic parameters were obtained from postnatal echocardiographic images within 24 h after birth. Results Eight patients died before 90 days of birth. Univariate analysis showed that the presence of continuous right to left shunt at the ductus, left pulmonary artery diameter of < 2.7 mm, right pulmonary artery diameter of < 3.3 mm, and left ventricular diastolic diameter of < 10.8 mm, were the predictors of poor prognosis. Multivariate logistic regression analysis showed that right pulmonary artery diameter of < 3.3 mm (adjusted OR 10.28, 95% C.I.: 1.15–249.19) and left ventricular diastolic diameter of < 10.8 mm (adjusted OR 7.86, 95% C.I.: 1.01–82.82) were predictors of poor prognosis. Conclusions This study revealed that the predictors of poor prognosis associated with CDH include smaller right pulmonary artery and left ventricular diastolic diameters. Retrospective Study-Level II.
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U2 - 10.1016/j.jpedsurg.2016.09.014
DO - 10.1016/j.jpedsurg.2016.09.014
M3 - Article
C2 - 27663123
AN - SCOPUS:84994777437
VL - 51
SP - 1926
EP - 1930
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
SN - 0022-3468
IS - 12
ER -