Ectopic pituitary adenoma in the cavernous sinus causing oculomotor nerve paresis: Case report

Nobuhiro Hata, Tooru Inoue, Toshiro Katsuta, Toru Iwaki

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A 24-year-old woman presented with a rare adrenocorticotropic hormone (ACTH)-positive pituitary adenoma in the cavernous sinus, manifesting as sudden onset of oculomotor nerve paresis. Neuroimaging revealed a tumor in the cavernous sinus bulging into the subdural space. There was no continuity between the tumor and the pituitary gland in the sella turcica. Gross total removal of the tumor was performed through the orbitozygomatic approach followed by stereotactic radiosurgery. The oculomotor nerve paresis was resolved. Histological examination revealed an adenoma positive for ACTH. Ectopic pituitary adenoma occurs mostly in the sphenoid sinus or the suprasellar region. This extremely rare case of ectopic macroadenoma in the cavernous sinus manifested as oculomotor nerve paresis without signs of Cushing's syndrome.

Original languageEnglish
Pages (from-to)399-403
Number of pages5
JournalNeurologia medico-chirurgica
Issue number8
Publication statusPublished - Aug 1 2003


All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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