TY - JOUR
T1 - Effect of bilayer morphology on the subgel phase formation
AU - Kinoshita, Masanao
AU - Kato, Satoru
AU - Takahashi, Hiroshi
N1 - Funding Information:
We thank Dr. Noboru Ohta for help in X-ray diffraction measurements. X-ray measurements were performed under approval of the Photon Factory Program Advisory Committee (Proposal No. 2003G138 and 2005G301). This study was partly supported by a grant-in-aid for High-Tech Research Center Project from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
PY - 2008/1
Y1 - 2008/1
N2 - We examined how morphology of bilayer assemblies affects the kinetics of the subgel phase formation in dimyristoylphosphatidylglycerol (DMPG) bilayers, which change their morphology depending on NaCl concentration. Quantitative analysis of the kinetics revealed that in flat sheet-like structures (bilayer sheets) the subgel phase forms in a simple two-state manner with the relaxation time of about 3 min at -10 °C while in vesicles it forms much slower under a multi-step process. Freeze-etch electron microscopic observations suggested that the kinetics of the subgel phase formation is directly correlated with the morphology of bilayer assemblies. It is likely that the bilayer sheet structure is more favorable to the subgel phase formation in DMPG bilayers than the vesicular structure.
AB - We examined how morphology of bilayer assemblies affects the kinetics of the subgel phase formation in dimyristoylphosphatidylglycerol (DMPG) bilayers, which change their morphology depending on NaCl concentration. Quantitative analysis of the kinetics revealed that in flat sheet-like structures (bilayer sheets) the subgel phase forms in a simple two-state manner with the relaxation time of about 3 min at -10 °C while in vesicles it forms much slower under a multi-step process. Freeze-etch electron microscopic observations suggested that the kinetics of the subgel phase formation is directly correlated with the morphology of bilayer assemblies. It is likely that the bilayer sheet structure is more favorable to the subgel phase formation in DMPG bilayers than the vesicular structure.
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U2 - 10.1016/j.chemphyslip.2007.09.005
DO - 10.1016/j.chemphyslip.2007.09.005
M3 - Article
C2 - 17983614
AN - SCOPUS:36348937366
SN - 0009-3084
VL - 151
SP - 30
EP - 40
JO - Chemistry and Physics of Lipids
JF - Chemistry and Physics of Lipids
IS - 1
ER -